Evidence map›Paper›PMID 33199995›Full record

ArticleExperimental and therapeutic medicine2020

Puerarin protects vascular smooth muscle cells from oxidized low-density lipoprotein-induced reductions in viability via inhibition of the p38 MAPK and JNK signaling pathways.

Yanwu Hu, Haitao Li, Ruili Li, Zijing Wu, Wenxin Yang, Wei Qu

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. The effective constituent puerarin, fromPharmaceutical biology · 2023
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Effects of swimming on the development of atherosclerosis in mice.American journal of translational research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanwu HuDepartment of Traditional Chinese Medicine, School of Medicine, Tonghua Normal University, Tonghua, Jilin 134002, P.R. China.
Haitao LiDepartment of Pharmacy, Affiliated Hospital, Changchun University of Chinese Medicine, Changchun, Jilin 130021, P.R. China.
Ruili LiDepartment of Pharmacy, Affiliated Hospital, Changchun University of Chinese Medicine, Changchun, Jilin 130021, P.R. China.
Zijing WuDepartment of Traditional Chinese Medicine, School of Medicine, Tonghua Normal University, Tonghua, Jilin 134002, P.R. China.
Wenxin YangDepartment of Traditional Chinese Medicine, School of Medicine, Tonghua Normal University, Tonghua, Jilin 134002, P.R. China.
Wei QuDepartment of Pharmacy, Affiliated Jiangyin Hospital of Southeast University Medical College, Jiangyin, Jiangsu 214400, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Puerarin belongs to the family of flavonoids extracted from

Indexed as

inflammationMAPK signaling pathwayoxidative stressoxidized low-density lipoproteinpuerarinvascular smooth muscle cells

Identifiers

PMID33199995
PMCPMC7664596

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.