Evidence map›Paper›PMID 33199992›Full record

ArticleExperimental and therapeutic medicine2020

Effect of sericin on the p38MAPK signaling pathway and NLRP3 inflammasome in the kidney of type 2 diabetic rats.

Donghui Liu, Cheng Chen, Dandan Wang, Zhihong Chen, Chengjun Song

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Polysaccharide fromMetabolites · 2026
    Article
  2. Sericin Protein: Structure, Properties, and Applications.Journal of functional biomaterials · 2024
    Review
  3. Article
  4. Article
  5. Heliyon · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Donghui LiuDepartment of Human Anatomy, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Cheng ChenDepartment of Physiology, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Dandan WangDepartment of Anatomy, Shijiazhuang Medical College, Shijiazhuang, Hebei 050599, P.R. China.
Zhihong ChenDepartment of Human Anatomy, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Chengjun SongDepartment of Human Anatomy, Chengde Medical University, Chengde, Hebei 067000, P.R. China.
Chengde Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to investigate the effects of sericin on the p38MAPK signaling pathway and nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in the kidney of rats with type 2 diabetes mellitus (T2DM). A total of 36 male Sprague-Dawley rats were randomly divided into the normal group, T2DM model group and sericin group (n=12 rats/group). A T2DM model was developed through intraperitoneal injection of streptozotocin (35 mg·kg

Indexed as

kidneyNLRP3 inflammasomep38MAPK signaling pathwaysericinT2DM

Identifiers

PMID33199992
PMCPMC7664612
OpenAlexW3096684230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.