Evidence map›Paper›PMID 33199837›Full record

ArticleLeukemia2021

Leukemic cells expressing NCOR1-LYN are sensitive to dasatinib in vivo in a patient-derived xenograft mouse model.

Toshihiro Tomii, Toshihiko Imamura, Kuniaki Tanaka, Itaru Kato, Azusa Mayumi, Emi Soma, Mio Yano, Kenichi Sakamoto, Takashi Mikami, Makiko Morita and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Leukemia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Toshihiro TomiiDepartment of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID http://orcid.org/0000-0001-9455-8037
Toshihiko ImamuraDepartment of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan. imamura@koto.kpu-m.ac.jp.ORCID http://orcid.org/0000-0002-5727-4470
Kuniaki TanakaDepartment of Pediatrics, Kyoto University, Kyoto, Japan.
Itaru KatoDepartment of Pediatrics, Kyoto University, Kyoto, Japan.ORCID http://orcid.org/0000-0002-2932-4960
Azusa MayumiDepartment of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Emi SomaDepartment of Clinical and Translational Physiology, Kyoto Pharmaceutical University, Kyoto, Japan.ORCID http://orcid.org/0000-0002-5660-7018
Mio YanoDepartment of Pediatrics, Kyoto City Hospital, Kyoto, Japan.
Kenichi SakamotoChildren's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
Takashi MikamiDepartment of Pediatrics, Kyoto University, Kyoto, Japan.
Makiko MoritaDepartment of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Nobutaka KiyokawaDepartment of Pediatric Hematology and Oncology Research, National Research Institute for Child Health and Development, Tokyo, Japan.
Keizo HoribeClinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Souichi AdachiDepartment of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tatsutoshi NakahataDrug Discovery Technology Development Office, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.
Junko TakitaDepartment of Pediatrics, Kyoto University, Kyoto, Japan.
Hajime HosoiDepartment of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Kyoto University · JPKyoto Prefectural University of Medicine · JPNational Center For Child Health and Development · JPKyoto City Hospital · JPKyoto Pharmaceutical University · JPNational Hospital Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorDasatinibDisease Models, AnimalHeterograftsHumansMiceNuclear Receptor Co-Repressor 1Precursor Cell Lymphoblastic Leukemia-LymphomaProtein Kinase Inhibitorssrc-Family KinasesDasatiniblyn protein-tyrosine kinaseNCOR1 protein, humanNuclear Receptor Co-Repressor 1Protein Kinase Inhibitorssrc-Family Kinases

Identifiers

PMID33199837
OpenAlexW3101537555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.