ArticleThe ISME journal2021
Potential virus-mediated nitrogen cycling in oxygen-depleted oceanic waters.
Article in The ISME journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 158 citations in OpenAlex.
- Three Decades of Soil NGlobal change biology · 2026Review
- Invertebrates gut viromes mediate microbial adaptation to pharmaceutical diversity under warming.Microbiome · 2026Article
- Bacteriophages in the Rhizosphere: Roles in Nutrient Cycling, Bacterial Community Structure, and Animal-Mediated Dispersal.MicrobiologyOpen · 2026Review
- Genome-resolved multi-omics provide new insights into microbial nitrogen utilization by the rumen microbiota.Microbiome · 2026Article
- Hi-C Links Reveal Viral Activity and Infection Within the Free-Living Microbial Community of a Secondary Chlorophyll Maximum in the Eastern Tropical North Pacific.Environmental microbiology · 2026Article
- Diversity and ecological potential of sediment viruses from Chinese continental shelf seas.NPJ biofilms and microbiomes · 2026Article
- The hidden role of rhizospheric viruses in promoting nitrogen fixation in soils.Nature communications · 2026Article
- PhaGCN_Cluster: A Scalable and Robust Framework for Automated Classification and Discovery of Viral Dark Matter from Metagenomes.Interdisciplinary sciences, computational life sciences · 2026Article
- Unveiling the hidden viral biodiversity and potential ecological functions with global coral holobiont virome database.NPJ biofilms and microbiomes · 2026Article
- Article
- Virus-encoded metabolism may support environmental stress adaptation of microbial hosts in an estuarine hypoxic zone.Frontiers in microbiology · 2026Article
- Coexistence of virome-encoded health-associated genes and pathogenic genes in global habitats.Applied and environmental microbiology · 2025Article
- Protein Set Transformer: a protein-based genome language model to power high-diversity viromics.Nature communications · 2025Article
- Viral ecogenomics across oxic and anoxic zones of the Yongle Blue Hole.Environmental microbiome · 2025Article
- Salinity-driven shifts in estuarine viral community composition and diversity near the Shenzhen coast.Applied and environmental microbiology · 2025Article
- Genomic analysis of the novel Stenotrophomonas phage vB_Srh_LBjhp91a, isolated from a Karst cave in China.Archives of virology · 2025Article
- LucaPCycle: Illuminating microbial phosphorus cycling in deep-sea cold seep sediments using protein language models.Nature communications · 2025Article
- Endemism shapes viral ecology and evolution in globally distributed hydrothermal vent ecosystems.Nature communications · 2025Article
- Expanding the potential soil carbon sink: unraveling carbon sequestration accessory genes in vermicompost phages.Applied and environmental microbiology · 2025Article
- Phages-bacteria interactions underlying the dynamics of polyhydroxyalkanoate-producing mixed microbial cultures via meta-omics study.mSystems · 2025Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Viruses play an important role in the ecology and biogeochemistry of marine ecosystems. Beyond mortality and gene transfer, viruses can reprogram microbial metabolism during infection by expressing auxiliary metabolic genes (AMGs) involved in photosynthesis, central carbon metabolism, and nutrient cycling. While previous studies have focused on AMG diversity in the sunlit and dark ocean, less is known about the role of viruses in shaping metabolic networks along redox gradients associated with marine oxygen minimum zones (OMZs). Here, we analyzed relatively quantitative viral metagenomic datasets that profiled the oxygen gradient across Eastern Tropical South Pacific (ETSP) OMZ waters, assessing whether OMZ viruses might impact nitrogen (N) cycling via AMGs. Identified viral genomes encoded six N-cycle AMGs associated with denitrification, nitrification, assimilatory nitrate reduction, and nitrite transport. The majority of these AMGs (80%) were identified in T4-like Myoviridae phages, predicted to infect Cyanobacteria and Proteobacteria, or in unclassified archaeal viruses predicted to infect Thaumarchaeota. Four AMGs were exclusive to anoxic waters and had distributions that paralleled homologous microbial genes. Together, these findings suggest viruses modulate N-cycling processes within the ETSP OMZ and may contribute to nitrogen loss throughout the global oceans thus providing a baseline for their inclusion in the ecosystem and geochemical models.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.