Evidence map›Paper›PMID 33199617›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

HOS15 is a transcriptional corepressor of NPR1-mediated gene activation of plant immunity.

Mingzhe Shen, Chae Jin Lim, Junghoon Park, Jeong Eun Kim, Dongwon Baek, Jaesung Nam, Sang Yeol Lee, Jose M Pardo, Woe-Yeon Kim, David Mackey and 1 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

  1. Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Mingzhe ShenDepartment of Horticulture and Crop Science, The Ohio State University, Columbus, OH 43210.ORCID 0000-0003-2898-1579
Chae Jin LimDivision of Applied Life Science (BK21 Plus Program), Plant Molecular Biology and Biotechnology Research Center, Institute of Agriculture and Life Science, Gyeongsang National University, 52828 Jinju, Republic of Korea.
Junghoon ParkDivision of Applied Life Science (BK21 Plus Program), Plant Molecular Biology and Biotechnology Research Center, Institute of Agriculture and Life Science, Gyeongsang National University, 52828 Jinju, Republic of Korea.ORCID 0000-0002-7209-2990
Jeong Eun KimDivision of Applied Life Science (BK21 Plus Program), Plant Molecular Biology and Biotechnology Research Center, Institute of Agriculture and Life Science, Gyeongsang National University, 52828 Jinju, Republic of Korea.
Dongwon BaekDivision of Applied Life Science (BK21 Plus Program), Plant Molecular Biology and Biotechnology Research Center, Institute of Agriculture and Life Science, Gyeongsang National University, 52828 Jinju, Republic of Korea.ORCID 0000-0001-8264-7550
Jaesung NamDepartment of Molecular Biotechnology, Dong-A University, 604-714 Busan, South Korea.ORCID 0000-0001-7673-6792
Sang Yeol LeeDivision of Applied Life Science (BK21 Plus Program), Plant Molecular Biology and Biotechnology Research Center, Institute of Agriculture and Life Science, Gyeongsang National University, 52828 Jinju, Republic of Korea.ORCID 0000-0002-8368-932X
Jose M PardoInstitute of Plant Biochemistry and Photosynthesis, Consejo Superior de Investigaciones Cientificas, 41092 Seville, Spain.ORCID 0000-0003-4510-8624
Woe-Yeon KimDivision of Applied Life Science (BK21 Plus Program), Plant Molecular Biology and Biotechnology Research Center, Institute of Agriculture and Life Science, Gyeongsang National University, 52828 Jinju, Republic of Korea.ORCID 0000-0001-9967-5929
David MackeyDepartment of Horticulture and Crop Science, The Ohio State University, Columbus, OH 43210; mackey.86@osu.edu djyun@konkuk.ac.kr.ORCID 0000-0002-0891-3061
Dae-Jin YunDepartment of Biomedical Science and Engineering, Konkuk University, 05029 Seoul, South Korea; mackey.86@osu.edu djyun@konkuk.ac.kr.ORCID 0000-0002-3638-6043
Gyeongsang National University · KRConsejo Superior de Investigaciones Científicas · ESDong-A University · KRKonkuk University · KRThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcriptional regulation is a complex and pivotal process in living cells. HOS15 is a transcriptional corepressor. Although transcriptional repressors generally have been associated with inactive genes, increasing evidence indicates that, through poorly understood mechanisms, transcriptional corepressors also associate with actively transcribed genes. Here, we show that HOS15 is the substrate receptor for an SCF/CUL1 E3 ubiquitin ligase complex (SCF

Indexed as

Gene Expression Regulation, PlantPlant ImmunityPlant Physiological PhenomenaTranscriptional ActivationArabidopsisChromosomal Proteins, Non-HistoneCo-Repressor ProteinsMultiprotein ComplexesPlant ProteinsProtein BindingUbiquitinationUbiquitin-Protein LigasesChromosomal Proteins, Non-HistoneCo-Repressor ProteinsMultiprotein ComplexesPlant ProteinsUbiquitin-Protein LigasescorepressorHOS15NPR1plant immunityubiquitin ligase

Identifiers

PMID33199617
PMCPMC7720166
OpenAlexW3104673335

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.