Evidence map›Paper›PMID 33199597›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Biophysical analysis of the structural evolution of substrate specificity in RuBisCO.

Saroj Poudel, Douglas H Pike, Hagai Raanan, Joshua A Mancini, Vikas Nanda, Rosalind E M Rickaby, Paul G Falkowski

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  3. Shelf-invading low-oxygen waters control Cenozoic organic carbon burial rates.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  10. Atomic view of photosynthetic metabolite permeability pathways and confinement in synthetic carboxysome shells.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Saroj PoudelEnvironmental Biophysics and Molecular Ecology Program, Department of Marine and Coastal Sciences, Rutgers University, New Brunswick, NJ 08901.
Douglas H PikeCenter for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, NJ 08854.
Hagai RaananEnvironmental Biophysics and Molecular Ecology Program, Department of Marine and Coastal Sciences, Rutgers University, New Brunswick, NJ 08901.
Joshua A ManciniEnvironmental Biophysics and Molecular Ecology Program, Department of Marine and Coastal Sciences, Rutgers University, New Brunswick, NJ 08901.
Vikas NandaCenter for Advanced Biotechnology and Medicine, Rutgers University, Piscataway, NJ 08854.ORCID 0000-0003-2786-8347
Rosalind E M RickabyDepartment of Earth Sciences, University of Oxford, OX1 3AN Oxford, United Kingdom.ORCID 0000-0002-6095-8419
Paul G FalkowskiEnvironmental Biophysics and Molecular Ecology Program, Department of Marine and Coastal Sciences, Rutgers University, New Brunswick, NJ 08901; falko@marine.rutgers.edu.
Rutgers, The State University of New Jersey · USUniversity of Oxford · GB

Funding

Shared Services Center NASA 80NSSC18M0093
6 · The paper itself

Abstract

Ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the most abundant enzyme on Earth. However, its catalytic rate per molecule of protein is extremely slow and the binding of the primary substrate, CO

Indexed as

Biophysical PhenomenaModels, MolecularProtein ConformationCarbon DioxideCatalysisModels, ChemicalMolecular Dynamics SimulationPhylogenyRibulose-Bisphosphate CarboxylaseSpectrum AnalysisSubstrate SpecificityCarbon DioxideRibulose-Bisphosphate Carboxylasebinding selectivityprotein engineeringprotein structural evolutionRuBisCO

Identifiers

PMID33199597
PMCPMC7720200
OpenAlexW3103722093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.