Evidence map›Paper›PMID 33199541›Full record

ArticleTobacco control2020

Transitions between cigarette, ENDS and dual use in adults in the PATH study (waves 1-4): multistate transition modelling accounting for complex survey design.

Andrew F Brouwer, Jihyoun Jeon, Jana L Hirschtick, Evelyn Jimenez-Mendoza, Ritesh Mistry, Irina V Bondarenko, Stephanie R Land, Theodore R Holford, David T Levy, Jeremy M G Taylor and 2 more

Open access · greenAbstract read
In one paragraph

Article in Tobacco control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 76 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Continuous associations of the brief Wisconsin Inventory of Smoking Dependence Motives with transitions between cigarette and e-cigarette use.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  8. COPD stage progression and regression: a multistate transition analysis of the COPDGene cohort.American journal of respiratory and critical care medicine · 2026
    Article
  9. Article
  10. Identifying Latent Classes of Dual Cigarette/ENDS Users Based on Motivations for ENDS Use: Product Substitution Versus Complementary Use.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  11. Urinary Tobacco and Nicotine Exposure Biomarkers as Predictors of Transitions between Cigarette and e-Cigarette Use in the Exhale Longitudinal Cohort Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Andrew F BrouwerEpidemiology, University of Michigan, Ann Arbor, Michigan, USA brouweaf@umich.edu.ORCID http://orcid.org/0000-0002-3779-5287
Jihyoun JeonEpidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Jana L HirschtickEpidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Evelyn Jimenez-MendozaEpidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Ritesh MistryHealth Behavior and Health Education, University of Michigan, Ann Arbor, Michigan, USA.
Irina V BondarenkoBiostatistics, University of Michigan, Ann Arbor, Michigan, USA.
Stephanie R LandTobacco Control Research Branch, National Cancer Institute Division of Cancer Control and Population Sciences, Rockville, Maryland, USA.
Theodore R HolfordBiostatistics, Yale University, New Haven, Connecticut, USA.
David T LevyOncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.ORCID http://orcid.org/0000-0001-5280-3612
Jeremy M G TaylorBiostatistics, University of Michigan, Ann Arbor, Michigan, USA.
Nancy L FleischerEpidemiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID http://orcid.org/0000-0002-4371-9133
Rafael MezaEpidemiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID http://orcid.org/0000-0002-1076-5037
University of Michigan · USGeorgetown University · USNational Cancer Institute · USYale University · US

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Eric R. Fearon · 1988 to 2026
$178.2M
Research Project 3: Modeling the Impact of Tobacco Control Policies on Polytobacco Use and Associated Health DisparitiesU54CA229974 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Mendez Emilien · 2018 to 2026
$39.2M
NCI NIH HHS P30 CA046592NCI NIH HHS U54 CA229974
6 · The paper itself

Abstract

introductionEven prior to 2018, electronic nicotine delivery systems (ENDS) began to dramatically change the landscape of tobacco products and product use patterns in the USA.

methodsUsing a Markov multistate transition model accounting for complex survey design, transition rates between never, non-current, cigarette, ENDS and dual use states were estimated for 23 253 adult participants in waves 1-4 (approximately 2013-2017) of the Population Assessment of Tobacco and Health study. We made short-term transition projections and estimated HRs for age, sex, race/ethnicity, education and income.

resultsCigarette use was persistent among adults, with 89.7% (95% CI 89.1% to 90.3%) of exclusive cigarette users and 86.1% (95% CI 84.4% to 87.9%) of dual users remaining cigarette users (either exclusive or dual) after one wave. In contrast, ENDS use was less persistent, with 72.1% (95% CI 69.6% to 74.6%) of exclusive ENDS users and 50.5% (95% CI 47.8% to 53.3%) of dual users remaining ENDS users (with or without cigarettes) after one wave. Exclusive ENDS users were more likely to start cigarette use after one wave than either never users (HR 25.2; 95% CI 20.9 to 30.5) or non-current users (HR 5.0; 95% CI 4.3 to 5.8). Dual users of ENDS and cigarettes were more likely to stop using cigarettes than exclusive cigarette users (HR 1.9; 95% CI 1.6 to 2.3). Transition rates varied among sociodemographic groups.

conclusionsMultistate transition models are an effective tool for uncovering and characterising longitudinal patterns and determinants of tobacco use from complex survey data. ENDS use among US adults was less persistent than cigarette use prior to 2018.

Indexed as

disparitieselectronic nicotine delivery devicesnon-cigarette tobacco productssurveillance and monitoring

Identifiers

PMID33199541
PMCPMC8124082
OpenAlexW3103827852

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.