Evidence map›Paper›PMID 33199428›Full record

ArticleBMJ open2020

COVID-19 outcomes in UK centre within highest health and wealth band: a prospective cohort study.

Gie Ken-Dror, Charles Wade, Shyam Sharma, Jessica Law, Cristina Russo, Aarti Sharma, Elizabeth Joy, Joshua John, Jonathan Robin, Sarah John and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Gie Ken-DrorInstitute of Cardiovascular Research, Royal Holloway University of London, Egham, UK.ORCID 0000-0003-3747-7112
Charles WadeDepartment of Clinical Neuroscience, Imperial College Healthcare NHS Trust, London, UK.
Shyam SharmaCollege of Medicine, University of Edinburgh, Edinburgh, Scotland.
Jessica LawDivision of Medicine, Ashford and Saint Peter's Hospitals NHS Foundation Trust, Chertsey, Surrey, UK.
Cristina RussoDivision of Medicine, Ashford and Saint Peter's Hospitals NHS Foundation Trust, Chertsey, Surrey, UK.
Aarti SharmaSchool of Medicine, Imperial College London, London, UK.
Elizabeth JoyDivision of Medicine, Ashford and Saint Peter's Hospitals NHS Foundation Trust, Chertsey, Surrey, UK.
Joshua JohnSchool of Medicine, Kings College London, London, UK.
Jonathan RobinDivision of Medicine, Ashford and Saint Peter's Hospitals NHS Foundation Trust, Chertsey, Surrey, UK.
Sarah JohnMurray Edwards College, University of Cambridge, Cambridge, UK.
Karim MahanaDivision of Medicine, Ashford and Saint Peter's Hospitals NHS Foundation Trust, Chertsey, Surrey, UK.
David FluckDivision of Medicine, Ashford and Saint Peter's Hospitals NHS Foundation Trust, Chertsey, Surrey, UK.
Paul BentleyDepartment of Brain Sciences, Imperial College London, London, UK.
Pankaj SharmaInstitute of Cardiovascular Research, Royal Holloway University of London, Egham, UK pankaj.sharma@rhul.ac.uk.
Ashford and St Peter's Hospitals NHS Foundation Trust · GBImperial College Healthcare NHS Trust · GBImperial College London · GBEdinburgh College · GBKing's College London · GBRoyal Holloway University of London · GBUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the characteristics and outcomes of hospitalised patients with COVID-19 from UK in the highest decile of health and gross regional products per capita.

designProspective cohort study.

settingRecruited all adult inpatients with laboratory-confirmed COVID-19 symptoms admitted to a single Surrey centre between March and April 2020. Extensive demographic details were documented. OUTCOME MEASURE: COVID-19 status of alive/dead and intensive care unit (ICU) status of yes/no.

participantsPatients with COVID-19 from Surrey centre UK (n=429).

results429 adult inpatients (mean age 70±18 years; men 56.4%) were included in this study, of whom, 19.1% required admission to ICU and 31.9% died. Adverse outcomes were associated with age (OR with each decade of years: 1.78, 95% CI 1.53 to 2.11, p<0.001 for mortality); male gender (OR=1.08, 95% CI 0.72 to 1.63, p=0.72, present in 70.7%, of admissions to ICU versus 53% of other cases, p=0.004); cardiac disease (OR=3.43, 95% CI 2.10 to 5.63, p<0.001), diabetes mellitus (OR=2.37, 95% CI 1.09 to 5.17, p=0.028) and dementia (OR=5.06, 95% CI 2.79 to 9.44, p<0.001). There was no significant impact of ethnicity or body mass index on disease outcome.

conclusionsDespite reports of worse outcomes in deprived regions, we show similar complication and mortality rates due to COVID-19 in an affluent and high life expectancy region.

Indexed as

InpatientsIntensive Care UnitsPandemicsSARS-CoV-2AgedAged, 80 and overCOVID-19FemaleHospitalizationHospital MortalityHumansMaleProspective StudiesRisk FactorsUnited KingdomCOVID-19epidemiologypublic health

Identifiers

PMID33199428
PMCPMC7670555
OpenAlexW3098747963

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.