Evidence map›Paper›PMID 33199388›Full record

ArticleAntimicrobial agents and chemotherapy2021

New Topoisomerase Inhibitors: Evaluating the Potency of Gepotidacin and Zoliflodacin in Fluoroquinolone-Resistant Escherichia coli upon

Sabine Schuster, Martina Vavra, Raphael Köser, John W A Rossen, Winfried V Kern

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Management and prevention of Neisseria meningitidis and Neisseria gonorrhoeae infections in the context of evolving antimicrobial resistance trends.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Sabine SchusterDivision of Infectious Diseases, Department of Medicine II, University Hospital and Medical Center, Freiburg, Germany sabine.schuster@uniklinik-freiburg.de.ORCID 0000-0002-8817-6224
Martina VavraDivision of Infectious Diseases, Department of Medicine II, University Hospital and Medical Center, Freiburg, Germany.
Raphael KöserDivision of Infectious Diseases, Department of Medicine II, University Hospital and Medical Center, Freiburg, Germany.
John W A RossenDepartment of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Winfried V KernDivision of Infectious Diseases, Department of Medicine II, University Hospital and Medical Center, Freiburg, Germany.
University Medical Center Freiburg · DEUniversity Medical Center Groningen · NLUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inactivating

Indexed as

Escherichia coliEscherichia coli ProteinsAcenaphthenesAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBarbituratesDrug Resistance, Multiple, BacterialFluoroquinolonesHeterocyclic Compounds, 3-RingIsoxazolesMorpholinesOxazolidinonesSpiro CompoundsTopoisomerase InhibitorsAcenaphthenesAcrB protein, E coliAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBarbituratesEscherichia coli ProteinsFluoroquinolonesgepotidacinHeterocyclic Compounds, 3-RingIsoxazolesMorpholinesOxazolidinonesSpiro CompoundsTopoisomerase InhibitorszoliflodacinAcrBclinical E. coli isolatesdrug effluxfluoroquinolonesgepotidacinRND-type transporterTolCYhiV (MdtF)zoliflodacin

Identifiers

PMID33199388
PMCPMC7849005
OpenAlexW3105441078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.