Evidence map›Paper›PMID 33199365›Full record

ArticleThe Journal of biological chemistry

K

Maurish Bukhari, Han Deng, Darren Sipes, Marisa Ruane-Foster, Kayla Purdy, Craig D Woodworth, Shantanu Sur, Damien S K Samways

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Ion Channels and Personalized Medicine in Gynecological Cancers.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Maurish BukhariDepartment of Biology, Clarkson University, Potsdam, New York, USA.
Han DengDepartment of Biology, Clarkson University, Potsdam, New York, USA.
Darren SipesDepartment of Biology, Clarkson University, Potsdam, New York, USA.
Marisa Ruane-FosterDepartment of Biology, Clarkson University, Potsdam, New York, USA.
Kayla PurdyDepartment of Biology, Clarkson University, Potsdam, New York, USA.
Craig D WoodworthDepartment of Biology, Clarkson University, Potsdam, New York, USA.
Shantanu SurDepartment of Biology, Clarkson University, Potsdam, New York, USA.
Damien S K SamwaysDepartment of Biology, Clarkson University, Potsdam, New York, USA. Electronic address: dsamways@clarkson.edu.
Clarkson University · US

Funding

Interaction of HPV with cells of the transformation zoneR15CA173703 · NCI · CLARKSON UNIVERSITY · PI WOODWORTH, CRAIG DUNCAN · 2013 to 2013
$436k
NCI NIH HHS R15 CA173703
6 · The paper itself

Abstract

The poor and nonselective penetration of current chemotherapeutics across the plasma membranes of cancer cells, which is necessary for the targeted disruption of the intracellular machinery, remains a major pharmaceutical challenge. In several cell types, including mast cells and macrophages, exposure to extracellular ATP is known to stimulate passive entry of large and otherwise membrane impermeable cationic dyes, which is usually attributed to conduction through ionotropic P2X receptors. Here, we report that elevations in cytosolic Ca

Indexed as

BenzimidazolesCytotoxinsBiological Transport, ActiveCell Line, TumorDNA, NeoplasmFemaleHumansIntermediate-Conductance Calcium-Activated Potassium ChannelsNeoplasm ProteinsUterine Cervical NeoplasmsBenzimidazolesCytotoxinsDNA, Neoplasmhoechst 32258Intermediate-Conductance Calcium-Activated Potassium ChannelsKCNN4 protein, humanNeoplasm ProteinsATPCa(2+)cancerdrug deliveryHoechstion channelK(Ca)3.1permeabilityplasma membrane

Identifiers

PMID33199365
PMCPMC7948979
OpenAlexW3101909196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.