Evidence map›Paper›PMID 33199356›Full record

ArticleInfection and immunity2021

Genetic Variation in Toll-Like Receptor 5 and Colonization with Flagellated Bacterial Vaginosis-Associated Bacteria.

Erin J Dela Cruz, Tina L Fiedler, Congzhou Liu, Matthew M Munch, Christina M Kohler, Antoinette R Oot, Jacqueline M Wallis, Junhui Wang, Anna Frishman, Kristina Garcia and 8 more

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Immunometabolic Analysis ofFrontiers in cellular and infection microbiology · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Erin J Dela CruzMedical Scientist Training Program, School of Medicine, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-3380-5353
Tina L FiedlerVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Congzhou LiuVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Matthew M MunchVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Christina M KohlerVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Antoinette R OotVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Jacqueline M WallisVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Junhui WangVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Anna FrishmanVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Kristina GarciaVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Andrew WiserVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Jennifer E BalkusVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Sujatha SrinivasanVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Jonathan L GolobVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.ORCID 0000-0003-0009-5815
Laura K SycuroDepartment of Microbiology, Immunology & Infectious Diseases, University of Calgary, Calgary, Alberta, Canada.
Jeanne M MarrazzoDivision of Infectious Diseases, Department of Medicine, University of Alabama School of Medicine, Birmingham, Alabama, USA.
Thomas R Hawn *Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
David N Fredricks *Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA dfredric@fredhutch.org.ORCID 0000-0003-2735-6800
Fred Hutch Cancer Center · USUniversity of Washington · USUniversity of Alabama at Birmingham · USUniversity of Calgary · CA

Funding

University of Washington Medical Scientist Training Program: MD/PhDT32GM007266 · NIGMS · UNIVERSITY OF WASHINGTON · PI HORWITZ, MARSHALL S. · 1985 to 2023
$30.4M
Urethral microbiome and non-gonococcal urethritis in men who have sex with men (MU19AI113173 · NIAID · UNIVERSITY OF WASHINGTON · PI MARRAZZO, JEANNE M · 2014 to 2018
$14.3M
The Role of Uncultivated Bacteria in Bacterial VaginosisR01AI061628 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI FREDRICKS, DAVID NEAL · 2006 to 2016
$6.6M
Novel Cultivation Methods for the Domestication of Vaginal BacteriaR01HG005816 · NHGRI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI FREDRICKS, DAVID NEAL · 2010 to 2012
$2.0M
Acquisition of Bacterial Vaginosis in LesbiansR56AI052228 · NIAID · UNIVERSITY OF WASHINGTON · PI MARRAZZO, JEANNE M · 2010 to 2010
$565k
NHGRI NIH HHS R01 HG005816NIAID NIH HHS R01 AI061628NIAID NIH HHS R56 AI052228NIAID NIH HHS U19 AI113173NIGMS NIH HHS T32 GM007266
6 · The paper itself

Abstract

Bacterial vaginosis (BV) is a vaginal dysbiotic condition linked to negative gynecological and reproductive sequelae. Flagellated bacteria have been identified in women with BV, including

Indexed as

AdolescentAdultCohort StudiesFemaleFlagellinGenes, BacterialGenetic VariationGenotypeHumansMiddle AgedMobiluncusToll-Like Receptor 5VaginaVaginosis, BacterialWashingtonYoung AdultFlagellinTLR5 protein, humanToll-Like Receptor 5bacterial vaginosisflagellamicrobiomeToll-like receptors

Identifiers

PMID33199356
PMCPMC8097276
OpenAlexW3100728266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.