Evidence map›Paper›PMID 33199329›Full record

ArticleClinical medicine (London, England)2020

Lesson of the month: Oxycodone-induced leukoencephalopathy: a rare diagnosis.

Eleanor Jones, Udayaraj Umasankar, Habeeba Mallu, Timothy Hampton, Angela Kulendran, Mehool Patel

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Clinical medicine (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eleanor JonesUniversity Hospital Lewisham, Lewisham, UK.
Udayaraj UmasankarUniversity Hospital Lewisham, Lewisham, UK udayaraj.umasankar@nhs.net.
Habeeba MalluUniversity Hospital Lewisham, Lewisham, UK.
Timothy HamptonUniversity Hospital Lewisham, Lewisham, UK.
Angela KulendranUniversity Hospital Lewisham, Lewisham, UK.
Mehool PatelUniversity Hospital Lewisham, Lewisham, UK.
University Hospital Lewisham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxycodone-induced leukoencephalopathy is a rare diagnosis that should be considered in unconscious patients with appropriate history. We describe a case of a 57-year-old unconscious woman who required intubation and did not respond to naloxone infusion. The unconsciousness was initially thought to be due to hypoxic brain injury. However, a further review of brain imaging showed characteristic features of oxycodone-induced leukoencephalopathy. We describe the pathological and radiological features of this condition, and provide a concise review of the limited literature on this condition. Accurate diagnosis of this condition will be valuable to clinicians and patients in terms of their medium-term and long-term prognosis, and potential for rehabilitation.

Indexed as

LeukoencephalopathiesOxycodoneBrainFemaleHumansMagnetic Resonance ImagingMiddle AgedUnconsciousnessOxycodonecerebral white matterheroinhypoxic brain injuryOxycodone leukoencephalopathytoxic leukoencephalopathy

Identifiers

PMID33199329
PMCPMC7687330
OpenAlexW3098423188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.