ArticleClinical medicine (London, England)2020
Raynaud's phenomenon.
Article in Clinical medicine (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- Raynaud's Phenomenon of the Nipple: Epidemiological, Clinical, Pathophysiological, and Therapeutic Characterization.International journal of environmental research and public health · 2024Pooled it
- Reprogramming of the lipid metabolism axis in systemic sclerosis: mechanism analysis and therapeutic potential.Clinical rheumatology · 2026Review
- Anterior segment oculomics in systemic sclerosis: reduced OCT-derived pupil diameter without iris morphology alterations.Frontiers in medicine · 2026Article
- Systemic Sclerosis in Kazakh Patients: A Preliminary Case-Control Immunogenetic Profiling Study.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025Article
- A comprehensive study on drug-related Raynaud's phenomenon based on the FDA adverse event reporting system.Scientific reports · 2025Article
- Radial Periosteal Distraction as a Novel Intervention for Raynaud Syndrome with Gangrene: A Case Report.The American journal of case reports · 2025Article
- Integrative exome sequencing and machine learning identify MICB and interferon pathway genes as contributors to SSc risk.Annals of the rheumatic diseases · 2025Article
- Effects of Audio-Guided Imagery on Raynaud Phenomenon in Connective Tissue Disease.ACR open rheumatology · 2025Article
- Cold responses and hormonal echoes: a comprehensive view of Raynaud's vascular dysfunction.Inflammopharmacology · 2025Review
- Deep inferior epigastric perforator flap breast reconstruction in patients with Raynaud's disease: a case series and literature review.Journal of surgical case reports · 2025Article
- Clinical Images: Magnetic resonance imaging changes of bone marrow edema in the hands in Raynaud phenomenon.ACR open rheumatology · 2025Article
- Investigating the association between SARS-CoV-2 infection, COVID-19 vaccination, and autoimmune diseases in a pediatric population: a comprehensive analysis.Pediatric rheumatology online journal · 2025Article
- Preparation and Evaluation of Tadalafil-Loaded Nanoemulgel for Transdermal Delivery in Cold-Induced Vasoconstriction: A Potential Therapy for Raynaud's Phenomenon.Pharmaceutics · 2025Article
- Article
- Microvascular and cerebrovascular alterations in Raynaud's phenomenon and fibromyalgia.Angiogenesis · 2025Article
- Cardiovascular Safety of Anti-CGRP Monoclonal Antibodies in Older Adults or Adults With Disability With Migraine.JAMA neurology · 2025Article
- Metastatic esophageal squamous cell carcinoma with paraneoplastic Raynaud phenomenon: a case report.AME case reports · 2025Article
- Raynaud's phenomenon during treatment with lisdexamfetamine: risk of cerebral vasospasm?Einstein (Sao Paulo, Brazil) · 2025Article
- Endometriosis, Raynaud's Syndrome, and Migraine: A Retrospective Study of 12 Million Women.Gynecologic and obstetric investigation · 2025Article
- Digital Ulcers and Microvascular Abnormalities Presenting As the Initial Manifestations of Pre-scleroderma.Cureus · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Raynaud's phenomenon (RP) is a common vasospastic condition which affects ~5% of the general population. The majority of individuals have primary RP; however, Raynaud's can also occur secondary to a broad range of underlying medical conditions and drug therapies. RP is a cardinal feature in patients with systemic sclerosis and is often the earliest symptom of the disease. Unlike primary RP, patients with secondary RP can develop persistent digital ischaemia, including ulcers and gangrene. Patients require a comprehensive clinical assessment and investigation, in particular, the detection of autoantibodies and nailfold capillaroscopic abnormalities. Non-pharmacological management is indicated in all patients. There are a wide range of available drug therapies to treat RP, including when complicated by digital ulceration, and surgical intervention is sometimes required. Future research is needed to understand the complex pathogenesis of RP and to measure the impact and severity of RP to develop optimised approaches to management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.