ArticleBMC medicine2020
Chlamydia trachomatis transmission between the oropharynx, urethra and anorectum in men who have sex with men: a mathematical model.
Article in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Sequential Sex Practices and the Likelihood of Bacterial Sexually Transmitted Infections and Urethritis in Men Who Have Sex With Women.Sexually transmitted diseases · 2026Article
- Prevalence of chlamydial, gonococcal and syphilis positivity by anatomical site and sex via self-collected biospecimens using at-home testing kits among a large and diverse cohort of men and women enrolled in the MACS/WIHS Combined Cohort Study (MWCCS) in the USA.Sexually transmitted infections · 2026Article
- Epidemiological Patterns of Genital Ulcer Disease and Human Immunodeficiency Virus Among Public Clinic Attendees in Mthatha, Eastern Cape, South Africa.Diseases (Basel, Switzerland) · 2025Article
- Switching From Dual to Monotherapy for Gonorrhea is Associated With a Halving of Gonococcal Resistance to Azithromycin-A Modelling Study of MSM in Belgium.Open forum infectious diseases · 2025Article
- Identifying High-Risk Populations for Sexually Transmitted Infections in Chinese Men Who Have Sex With Men: A Cluster Analysis.Open forum infectious diseases · 2025Article
- Estimating Partnership Duration among MSM in Belgium-A Modeling Study.Infectious disease reports · 2024Article
- Sexually transmitted coinfections among at-risk HIV-positive MSM: implications for optimal preemptive treatment.Frontiers in medicine · 2024Article
- Incidence and Duration of Pharyngeal Chlamydia Among a Cohort of Men Who Have Sex With Men.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Controversies and evidence on Chlamydia testing and treatment in asymptomatic women and men who have sex with men: a narrative review.BMC infectious diseases · 2022Review
- Potential effect of antiseptic mouthwash on the incidence ofBMJ open · 2021Article
- Modelling the multiple anatomical site transmission of Mycoplasma genitalium among men who have sex with men in Australia.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundIt has been presumed that Chlamydia trachomatis is transmitted between men only through anal or oral sex, but no mathematical models have tested this presumption.
methodsTo test this presumption, we created 20 compartmental mathematical models of different sexual practices that included both oral and anal sex and calibrated these models to the observed rates of Chlamydia trachomatis infection at three anatomical sites from 4888 men who have sex with men (MSM) in Melbourne Sexual Health Centre during 2018-2019.
resultsA model that included only oral and anal sex could replicate the observed rates of single-site infection at the oropharynx, urethra and rectum alone, but could not replicate infection at more than one of these sites (multisite). However, if we included transmission from sexual practices that followed one another in the same sexual episode (e.g. saliva contamination of the penis from oral sex transmitting chlamydia to the rectum by anal sex), we significantly improved the calibration of multisite infection rates substantially.
conclusionsOur modelling study suggests that transmission routes other than just oral and anal sex are necessary to explain the high rate of Chlamydia trachomatis infection at more than one site.
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