Evidence map›Paper›PMID 33198722›Full record

ArticleBMC pulmonary medicine2020

Rapidly progressive metastatic cholangiocarcinoma in a postpartum patient with cystic fibrosis: a case report.

Sara W Carson, Kelly E Craven, David Nauen, Kristina Montemayor, Mark Yarchoan, William R Burns, Christian A Merlo, Natalie E West

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pulmonary medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Postpartum related intrahepatic cholangiocarcinoma withJournal of gastrointestinal oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara W CarsonDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 E. Monument St 5th Floor, Baltimore, MD, 21205, USA. scarson6@jhmi.edu.ORCID http://orcid.org/0000-0002-3848-1327
Kelly E CravenDepartment of Pathology, Johns Hopkins University, Baltimore, MD, USA.
David NauenDepartment of Pathology, Johns Hopkins University, Baltimore, MD, USA.
Kristina MontemayorDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 E. Monument St 5th Floor, Baltimore, MD, 21205, USA.
Mark YarchoanDepartment of Oncology, Johns Hopkins University, Baltimore, MD, USA.
William R BurnsDepartment of Surgery, Division of Surgical Oncology, Johns Hopkins University, Baltimore, MD, USA.
Christian A MerloDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 E. Monument St 5th Floor, Baltimore, MD, 21205, USA.
Natalie E WestDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 E. Monument St 5th Floor, Baltimore, MD, 21205, USA.

Funding

Tumor Antigens for Individual Signatures and TherapyP50CA062924 · NCI · JOHNS HOPKINS UNIVERSITY · PI LENNON, ANNE MARIE · 1993 to 2022
$54.6M
MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Cystic Fibrosis Foundation WEST17Y5NCI NIH HHS P50 CA062924NHLBI NIH HHS T32HL007534
6 · The paper itself

Abstract

backgroundCholangiocarcinoma is a rare gastrointestinal malignancy that arises within the intrahepatic, perihilar, and/or extrahepatic bile ducts. Individuals with cystic fibrosis are at increased risk for gastrointestinal malignancies. The most common gastrointestinal malignancy in cystic fibrosis is colon cancer, but other gastrointestinal malignancies also occur at greater rates than the general population. CASE PRESENTATION: We present a case of a rapidly progressive metastatic intrahepatic cholangiocarcinoma in an individual with cystic fibrosis who was 5 months postpartum, incidentally found while undergoing a lung transplantation evaluation.

conclusionA heightened clinical awareness of gastrointestinal malignancies, beyond colon cancer, in individuals with cystic fibrosis is warranted. It remains unclear if pregnancy is an additional risk factor for gastrointestinal malignancies in cystic fibrosis.

Indexed as

AdultBile Duct NeoplasmsBile Ducts, IntrahepaticCholangiocarcinomaCystic FibrosisFatal OutcomeFemaleHumansIncidental FindingsNeoplasm MetastasisPostpartum PeriodCase reportCholangiocarcinomaCystic fibrosis, pregnancyGastrointestinal cancer

Identifiers

PMID33198722
PMCPMC7670772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.