ArticleBMC infectious diseases2020
Evolution of comorbidities in people living with HIV between 2004 and 2014: cross-sectional analyses from ANRS CO3 Aquitaine cohort.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- CircRNA profiles of extracellular vesicle-enriched fractions from ART suppressed pregnant women living with HIV identifies interactome networks key to inflammation and viral latency.Journal of translational medicine · 2026Article
- The prevalence of comorbidity among people living with HIV/AIDS in Guyana: a cross-sectional study.IJID regions · 2026Article
- Moderate to Severe Impairment of DlAnnals of the American Thoracic Society · 2025Article
- Plasma Proteomic Signature as a Predictor of Age Advancement in People Living With HIV.Aging cell · 2025Article
- Article
- Traditional Chinese medicine for HIV-related chronic comorbidities: evidence and potential therapeutic mechanisms.Frontiers in pharmacology · 2025Review
- Association of Integrase Strand Transfer Inhibitor-Based Antiretroviral Therapy With Blood Pressure and Sustained Hypertension in People With Human Immunodeficiency Virus.American journal of hypertension · 2024Article
- Antiretroviral Therapy and Cardiovascular Risk in People With HIV in the United States-An Updated Analysis.Open forum infectious diseases · 2024Article
- What Women with HIV Know about Heart Health and Cardiovascular Risk and Intervention Preferences.International journal of environmental research and public health · 2024Article
- The Intersection of HIV and Pulmonary Vascular Health: From HIV Evolution to Vascular Cell Types to Disease Mechanisms.Journal of vascular diseases · 2024Article
- Physical activity and survival in chronic comorbidity among adult HIV patients in Ethiopia: a prospective cohort study.BMC infectious diseases · 2023Article
- Hepatocyte-Specific Triggering of Hepatic Stellate Cell Profibrotic Activation by Apoptotic Bodies: The Role of Hepatoma-Derived Growth Factor, HIV, and Ethanol.International journal of molecular sciences · 2023Article
- Body Mass Index but not Physical Activity Level Moderates Lowered Cardiac Baroreflex Sensitivity in People Living with HIV.International journal of exercise science · 2023Article
- Pericyte infection by HIV-1: a fatal attraction.Retrovirology · 2022Review
- Weight of Clinical and Social Determinants of Metabolic Syndrome in People Living with HIV.Viruses · 2022Article
- A comprehensive analysis of excess depressive disorder in women and men living with HIV in France compared to the general population.Scientific reports · 2022Article
- Weight Change and Predictors of Weight Change Among Patients Initiated on Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide or Bictegravir/Emtricitabine/Tenofovir Alafenamide: A Real-World Retrospective Study.Journal of health economics and outcomes research · 2021Article
- Gut Leakage of Fungal-Related Products: Turning Up the Heat for HIV Infection.Frontiers in immunology · 2021Review
- Corticosteroids Use and Incidence of Severe Infections in People Living with HIV Compared to a Matched Population.Journal of the International Association of Providers of AIDS CareArticle
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundThe objective of the study was to describe the evolution of chronic non-AIDS related diseases and their risk factors, in patients living with HIV (PLHIV) in the French ANRS CO3 Aquitaine prospective cohort, observed both in 2004 and in 2014 in order to improve long-term healthcare management.
methodsThe ANRS CO3 Aquitaine cohort prospectively collects epidemiological, clinical, biological and therapeutic data on PLHIV in the French Aquitaine region. Two cross sectional analyses were performed in 2004 and 2014, to investigate the patient characteristics, HIV RNA, CD4 counts and prevalence of some common comorbidities and treatment.
results2138 PLHIV (71% male, median age 52.2 years in 2014) were identified for inclusion in the study, including participants who were registered in the cohort with at least one hospital visit recorded in both 2004 and 2014. Significant increases in the prevalence of diagnosed chronic kidney disease (CKD), bone fractures, cardiovascular events (CVE), hypertension, diabetes and dyslipidaemia, as well as an increase in treatment or prevention for these conditions (statins, clopidogrel, aspirin) were observed. It was also reflected in the increase in the proportion of patients in the "high" or "very high" risk groups of the disease risk scores for CKD, CVE and bone fracture score.
conclusionsBetween 2004 and 2014, the aging PLHIV population identified in the French ANRS CO3 Aquitaine prospective cohort experienced an overall higher prevalence of non-HIV related comorbidities, including CKD and CVD. Long-term healthcare management and long-term health outcomes could be improved for PLHIV by: careful HIV management according to current recommendations with optimal selection of antiretrovirals, and early management of comorbidities through recommended lifestyle improvements and preventative measures.
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