Evidence map›Paper›PMID 33198587›Full record

ArticleThyroid : official journal of the American Thyroid Association2021

Early Diagnosis and Treatment of an Infant with a Novel Thyroid Hormone Receptor α Gene (pC380SfsX9) Mutation.

Ary E Furman, Alexandra M Dumitrescu, Samuel Refetoff, Roy E Weiss

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ary E FurmanDepartment of Medicine, Miller School of Medicine, University of Miami, Miami, Florida, USA.
Alexandra M DumitrescuDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
Samuel RefetoffDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
Roy E WeissDepartment of Medicine, Miller School of Medicine, University of Miami, Miami, Florida, USA.
University of Chicago · USUniversity of Miami · US

Funding

THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERSR01DK015070 · NIDDK · UNIVERSITY OF CHICAGO · PI ANTONIO C BIANCO, Alexandra Mihaela Dumitrescu · 1986 to 2026
$8.1M
Mouse Sbp2 deficiency models the multi-system syndrome of human SBP2 defectsR01DK110322 · NIDDK · UNIVERSITY OF CHICAGO · PI DUMITRESCU, ALEXANDRA MIHAELA · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK015070NIDDK NIH HHS R01 DK110322
6 · The paper itself

Abstract

Resistance to thyroid hormone alpha (RTHα) is caused by mutations in thyroid hormone receptor α (

Indexed as

ConstipationDevelopmental DisabilitiesEarly DiagnosisEarly Medical InterventionFemaleHumansInfantMegalencephalyMuscle HypotoniaMutationThyroid Hormone Receptors alphaThyroid Hormone Resistance SyndromeThyroxineThyroid Hormone Receptors alphaThyroxinedominant negative effectdyshormonogenesisgeneticsresistance to thyroid hormone alphathyroid hormone receptor alpha

Identifiers

PMID33198587
PMCPMC8215396
OpenAlexW3101967374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.