Evidence map›Paper›PMID 33198355›Full record

ReviewJournal of clinical medicine2020

Characteristics, Management, and Outcomes of Acute Coronary Syndrome Patients with Cancer.

Valentina Milazzo, Nicola Cosentino, Jeness Campodonico, Claudia Lucci, Daniela Cardinale, Carlo M Cipolla, Giancarlo Marenzi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Cardio-Oncology and Multi-Imaging Modalities.Journal of clinical medicine · 2025
    Review
  3. The impact of different dietary flavonoids on the risk of coronary heart disease in cancer patients and that on the prognosis of patients with cancer and coronary heart disease.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. What to Do When There Is Something Unexpected?Life (Basel, Switzerland) · 2024
    Article
  8. Cardiovascular Interventions in Patients With Active and Advanced Malignancy: An Updated Review.Journal of community hospital internal medicine perspectives · 2024
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Cancer-Associated Atherothrombosis: The Challenge.The International journal of angiology : official publication of the International College of Angiology, Inc · 2021
    Review
  15. Article
  16. The Radiologist as a Gatekeeper in Chest Pain.International journal of environmental research and public health · 2021
    Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Valentina MilazzoCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Nicola CosentinoCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Jeness CampodonicoCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Claudia LucciCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0002-7188-737X
Daniela CardinaleCardioncology Unit, European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0002-4038-8033
Carlo M CipollaCardiology Division, European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Giancarlo MarenziCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0003-4410-4461
Centro Cardiologico Monzino · ITEuropean Institute of Oncology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with cancer are at increased risk of cardiovascular disease, with a reported prevalence of acute coronary syndrome (ACS) ranging from 3% to 17%. The increased risk of ACS in these patients seems to be due to the complex interaction of shared cardiovascular risk factors, cancer type and stage, and chemotherapeutic and radiotherapy regimens. The management of ACS in patients with cancer is a clinical challenge, particularly due to cancer's unique pathophysiology, which makes it difficult to balance thrombotic and bleeding risks in this specific patient population. In addition, patients with cancer have largely been excluded from ACS trials. Hence, an evidence-based treatment for ACS in this group of patients is unknown and only a limited proportion of them is treated with antiplatelets or invasive revascularization, despite initial reports suggesting their beneficial prognostic effects in cancer patients. Finally, cancer patients experiencing ACS are also at higher risk of in-hospital and long-term mortality as compared to non-cancer patients. In this review, we will provide an overview on the available evidence of the relationship between ACS and cancer, in terms of clinical manifestations, possible underlying mechanisms, and therapeutic and prognostic implications.

Indexed as

acute coronary syndromecancerchemotherapyprognosis

Identifiers

PMID33198355
PMCPMC7696544
OpenAlexW3105687091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.