Evidence map›Paper›PMID 33198325›Full record

ArticleInternational journal of molecular sciences2020

Antibiofilm Properties of Temporin-L on

Angela Di Somma, Federica Recupido, Arianna Cirillo, Alessia Romano, Alessandra Romanelli, Sergio Caserta, Stefano Guido, Angela Duilio

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  6. Natural antibiotics against antimicrobial resistance: sources and bioinspired delivery systems.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Forced Wetting Properties of Bacteria-Laden Droplets Experiencing Initial Evaporation.Langmuir : the ACS journal of surfaces and colloids · 2023
    Article
  11. Temporins: Multifunctional Peptides from Frog Skin.International journal of molecular sciences · 2023
    Review
  12. Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Angela Di SommaDepartment of Chemical Science, University of Naples "Federico II", Via Cinthia, 80126 Naples, Italy.ORCID 0000-0003-4916-7875
Federica RecupidoDivision of Chemical Technology, School of Chemistry, Aristotle University of Thessaloniki, University Box 116, 54 124 Thessaloniki, Greece.
Arianna CirilloCEINGE-Biotecnologie Avanzate, 80145 Naples, Italy.
Alessia RomanoCEINGE-Biotecnologie Avanzate, 80145 Naples, Italy.
Alessandra RomanelliDepartment of Pharmaceutical Sciences, University of Milan, Via Venezian 21, 20133 Milan, Italy.ORCID 0000-0002-7609-4061
Sergio CasertaDepartment of Chemical, Materials and Industrial Production Engineering, University of Naples "Federico II", Piazzale V. Tecchio 80, 80125 Naples, Italy.ORCID 0000-0002-4400-0059
Stefano GuidoDepartment of Chemical, Materials and Industrial Production Engineering, University of Naples "Federico II", Piazzale V. Tecchio 80, 80125 Naples, Italy.
Angela DuilioDepartment of Chemical Science, University of Naples "Federico II", Via Cinthia, 80126 Naples, Italy.
Ceinge Biotecnologie Avanzate (Italy) · ITUniversity of Naples Federico II · ITAristotle University of Thessaloniki · GRUniversity of Milan · IT

Funding

"Identification and characterization of novel antitumoral/antimicrobial insect-derived peptides: a multidisciplinary, integrated approach from in silico to in vivo". PRIN 2017Ministero dell'Istruzione, dell'Università e della Ricerca ARS01_00597 Project "NAOCON
6 · The paper itself

Abstract

Biofilms consist of a complex microbial community adhering to biotic or abiotic surfaces and enclosed within a protein/polysaccharide self-produced matrix. The formation of this structure represents the most important adaptive mechanism that leads to antibacterial resistance, and therefore, closely connected to pathogenicity. Antimicrobial peptides (AMPs) could represent attractive candidates for the design of new antibiotics because of their specific characteristics. AMPs show a broad activity spectrum, a relative selectivity towards their targets (microbial membranes), the ability to act on both proliferative and quiescent cells, a rapid mechanism of action, and above all, a low propensity for developing resistance. This article investigates the effect at subMIC concentrations of Temporin-L (TL) on biofilm formation in

Indexed as

Anti-Bacterial AgentsAntimicrobial Cationic PeptidesBacterial AdhesionBiofilmsBiomassDrug Resistance, BacterialMicrobial Sensitivity TestsMicrofluidicsMicroscopy, ConfocalPolymersPolysaccharides, BacterialPseudomonas fluorescensShear StrengthStress, MechanicalSurface PropertiesAnti-Bacterial AgentsAntimicrobial Cationic PeptidesPolymersPolysaccharides, Bacterialtemporinantimicrobial peptidebiofilmbiofilm formation inhibitiondynamic and static condition

Identifiers

PMID33198325
PMCPMC7696879
OpenAlexW3105680998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.