Evidence map›Paper›PMID 33198295›Full record

ArticleNutrients2020

High Salt Diet Impacts the Risk of Sarcopenia Associated with Reduction of Skeletal Muscle Performance in the Japanese Population.

Yasuko Yoshida, Keisei Kosaki, Takehito Sugasawa, Masahiro Matsui, Masaki Yoshioka, Kai Aoki, Tomoaki Kuji, Risuke Mizuno, Makoto Kuro-O, Kunihiro Yamagata and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

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  20. Nutritional Influences on Locomotive Syndrome.Journal of clinical medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yasuko YoshidaDepartment of Clinical Laboratory Science, Faculty of Health Sciences, Tsukuba International University, Ibarak 300-0051, Japan.
Keisei KosakiFaculty of Sport Sciences, Waseda University, Saitama 359-1192, Japan.
Takehito SugasawaLaboratory of Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki 305-8577, Japan.
Masahiro MatsuiJapan Society for the Promotion of Science, Tokyo 102-0083, Japan.
Masaki YoshiokaGraduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8577, Japan.
Kai AokiGraduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8577, Japan.ORCID 0000-0003-1872-099X
Tomoaki KujiGraduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8577, Japan.
Risuke MizunoFaculty of Veterinary Medicine, Okayama University of Science, Ehime 794-8555, Japan.
Makoto Kuro-ODivision of Anti-aging Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi 329-0431, Japan.
Kunihiro YamagataDepartment of Nephrology, Faculty of Medicine, University of Tsukuba, Ibaraki 305-8577, Japan.
Seiji MaedaFaculty of Health and Sport Sciences, University of Tsukuba, Ibaraki 305-8577, Japan.
Kazuhiro TakekoshiLaboratory of Sports Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki 305-8577, Japan.
University of Tsukuba · JPJichi Medical University · JPOkayama University of Science · JP

Funding

Japan Society for the Promotion of Science 18K17975Japan Society for the Promotion of Science 19H03995Japan Society for the Promotion of Science 19J01099Japan Society for the Promotion of Science 20J20892
6 · The paper itself

Abstract

The World Health Organization has recommended 5 g/day as dietary reference intakes for salt. In Japan, the averages for men and women were 11.0 g/day and 9.3 g/day, respectively. Recently, it was reported that amounts of sodium accumulation in skeletal muscles of older people were significantly higher than those in younger people. The purpose of this study was to investigate whether the risk of sarcopenia with decreased muscle mass and strength was related to the amount of salt intake. In addition, we investigated its involvement with renalase. Four groups based on age and salt intake ("younger low-salt," "younger high-salt," "older low-salt," and "older high-salt") were compared. Stratifying by age category, body fat percentage significantly increased in high-salt groups in both younger and older people. Handgrip strength/body weight and chair rise tests of the older high-salt group showed significant reduction compared to the older low-salt group. However, there was no significant difference in renalase concentrations in plasma. The results suggest that high-salt intake may lead to fat accumulation and muscle weakness associated with sarcopenia. Therefore, efforts to reduce salt intake may prevent sarcopenia.

Indexed as

AgedAgingBody CompositionCystatin CFemaleHand StrengthHumansInterleukin-6JapanLinear ModelsMaleMiddle AgedMultivariate AnalysisMuscle, SkeletalSarcopeniaSodium ChlorideCystatin CInterleukin-6Sodium ChlorideSodium Chloride, Dietarybody fat percentagechair rise testknee extensor muscle strengthlong seat type body anteflexionmaximum gait speedrenalasesaltsarcopeniasingle-leg stance time

Identifiers

PMID33198295
PMCPMC7696631
OpenAlexW3099605819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.