Evidence map›Paper›PMID 33198146›Full record

ArticleMolecules (Basel, Switzerland)2020

A Methanol Extract of

Imene Ben Toumia, Mansour Sobeh, Marco Ponassi, Barbara Banelli, Anas Dameriha, Michael Wink, Leila Chekir Ghedira, Camillo Rosano

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Molecules (Basel, Switzerland) · 2024
    Review
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  6. Molecules (Basel, Switzerland) · 2023
    Review
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  10. Cardioprotective Effect ofMolecules (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Imene Ben ToumiaUnit of Bioactive Natural Substances and Biotechnology UR17ES47, Faculty of Dental Medicine of Monastir, University of Monastir, Avicenne Street, 5000 Monastir, Tunisia.ORCID 0000-0003-2194-8741
Mansour SobehInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany.
Marco PonassiIRCCS Policlinico San Martino, Largo R. Benzi 10, I-16132 Genova, Italy.
Barbara BanelliIRCCS Policlinico San Martino, Largo R. Benzi 10, I-16132 Genova, Italy.ORCID 0000-0003-1505-7141
Anas DamerihaInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany.ORCID 0000-0002-6793-3732
Michael WinkInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany.ORCID 0000-0002-7875-4510
Leila Chekir GhediraUnit of Bioactive Natural Substances and Biotechnology UR17ES47, Faculty of Dental Medicine of Monastir, University of Monastir, Avicenne Street, 5000 Monastir, Tunisia.
Camillo RosanoIRCCS Policlinico San Martino, Largo R. Benzi 10, I-16132 Genova, Italy.ORCID 0000-0003-2949-9215
Heidelberg University · DEOspedale Policlinico San Martino · ITUniversity of Monastir · TN

Funding

Italian Ministry of Health RC-2020
6 · The paper itself

Abstract

Colorectal cancer is a malignancy with a high incidence. Currently, the drugs used in chemotherapy are often accompanied by strong side effects. Natural secondary metabolites can interfere with chemotherapeutic drugs and intensify their cytotoxic effects. This study aimed to profile the secondary metabolites from the methanol extract of

Indexed as

Drug Resistance, NeoplasmAntineoplastic Agents, PhytogenicAntineoplastic Combined Chemotherapy ProtocolsApoptosisATP-Binding Cassette, Sub-Family C ProteinsATP Binding Cassette Transporter, Subfamily BCaco-2 CellsCaspasesCell ProliferationColorectal NeoplasmsDipsacaceaeDoxorubicinDrug CombinationsDrug Resistance, MultipleHumansInhibitory Concentration 50ABCB1 protein, humanAntineoplastic Agents, PhytogenicATP-Binding Cassette, Sub-Family C ProteinsATP Binding Cassette Transporter, Subfamily BCaspasesDoxorubicinDrug CombinationsMethanolmultidrug resistance-associated protein 1Plant ExtractsPolyphenolsCaco-2doxorubicinmultidrug resistanceScabiosa atropurpurea

Identifiers

PMID33198146
PMCPMC7697796
OpenAlexW3100403004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.