Evidence map›Paper›PMID 33198142›Full record

ArticleInternational journal of environmental research and public health2020

Understanding the Relationship between Environmental Arsenic and Prostate Cancer Aggressiveness among African-American and European-American Men in North Carolina.

Humberto Parada, Tianying Wu, Rebecca C Fry, Laura Farnan, Gary J Smith, James L Mohler, Jeannette T Bensen

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Humberto ParadaDivision of Epidemiology & Biostatistics, School of Public Health, San Diego State University, San Diego, CA 92182, USA.ORCID 0000-0001-6562-8577
Tianying WuDivision of Epidemiology & Biostatistics, School of Public Health, San Diego State University, San Diego, CA 92182, USA.ORCID 0000-0003-1679-3511
Rebecca C FryEnvironmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Laura FarnanDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Gary J SmithDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.
James L MohlerDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14203, USA.ORCID 0000-0002-7726-3795
Jeannette T BensenLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
STOCHASTIC ANALYSIS OF FLOW AND TRANSPORT PHENOMENAP42ES005948 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRY, REBECCA · 1992 to 2017
$45.4M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Research Education CoreU54CA132384 · NCI · SAN DIEGO STATE UNIVERSITY · PI CRIPPS, RICHARD MATTHEW, CROWE, SHEILA E. · 2008 to 2022
$20.7M
Research Education CoreU54CA132379 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ARREDONDO, ELVA M, CROWE, SHEILA E. · 2008 to 2021
$16.1M
San Diego Resource Center for advancing Alzheimer's Research in Minority Seniors (ARMS)P30AG059299 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Tala Al-Rousan · 2018 to 2026
$7.4M
Red Blood Cell Polyunsaturated Fatty Acids and Breast Cancer Mortality in the Women's Healthy Eating and Living (WHEL) StudyK01CA234317 · NCI · SAN DIEGO STATE UNIVERSITY · PI PARADA, HUMBERTO · 2019 to 2023
$928k
NCI NIH HHS K01 CA234317NCI NIH HHS P30 CA016086NCI NIH HHS U54 CA132379NCI NIH HHS U54 CA132384NIA NIH HHS P30AG05929NIA NIH HHS P30 AG059299NIEHS NIH HHS P30 ES010126NIEHS NIH HHS P42 ES005948
6 · The paper itself

Abstract

High-level exposure to arsenic, a known carcinogen and endocrine disruptor, is associated with prostate cancer (PCa) mortality. Whether low-level exposure is associated with PCa aggressiveness remains unknown. We examined the association between urinary arsenic and PCa aggressiveness among men in North Carolina. This cross-sectional study included 463 African-American and 491 European-American men with newly diagnosed, histologically confirmed prostate adenocarcinoma. PCa aggressiveness was defined as low aggressive (Gleason score < 7, stage = cT1-cT2, and PSA < 10 ng/mL) versus intermediate/high aggressive (all other cases). Total arsenic and arsenical species (inorganic arsenic (iAs

Indexed as

AdenocarcinomaArsenicBlack or African AmericanEnvironmental ExposureProstatic NeoplasmsWhite PeopleCross-Sectional StudiesHumansMaleNorth CarolinaRace FactorsUnited StatesArseniccancerenvironmental arsenicinorganic arsenicprostate

Identifiers

PMID33198142
PMCPMC7697081

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.