Evidence map›Paper›PMID 33197638›Full record

Observational studyAnaesthesia, critical care & pain medicine2021

A novel, automated, quantification of abnormal lung parenchyma in patients with COVID-19 infection: Initial description of feasibility and association with clinical outcome.

Eric Noll, Luc Soler, Mickael Ohana, Pierre-Olivier Ludes, Julien Pottecher, Elliott Bennett-Guerrero, Francis Veillon, Bernard Goichot, Francis Schneider, Nicolas Meyer and 1 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Anaesthesia, critical care & pain medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Eric NollDepartment of Anesthesiology and Intensive Care, Hautepierre Hospital, Strasbourg University Hospital, France. Electronic address: eric.noll@chru-strasbourg.fr.
Luc SolerDigestive and Endocrine Surgery Department, Nouvel Hôpital Civil, Strasbourg, France; Visible Patient, Strasbourg, France.
Mickael OhanaDepartment of Radiology, Nouvel Hôpital Civil, Strasbourg University Hospital, France.
Pierre-Olivier LudesDepartment of Anesthesiology and Intensive Care, Hautepierre Hospital, Strasbourg University Hospital, France; Equipe d'Accueil 3072, Medical School, Strasbourg University, Strasbourg, France.
Julien PottecherDepartment of Anesthesiology and Intensive Care, Hautepierre Hospital, Strasbourg University Hospital, France; Equipe d'Accueil 3072, Medical School, Strasbourg University, Strasbourg, France.
Elliott Bennett-GuerreroDepartment of Anesthesiology, Stony Brook Medicine, New-York, USA.
Francis VeillonDepartment of Radiology, Hautepierre Hospital, Strasbourg University Hospital, France.
Bernard GoichotDepartment of Internal Medicine, Hautepierre Hospital, Strasbourg University Hospital, France.
Francis SchneiderMédecine Intensive-Réanimation, Hautepierre Hospital, Strasbourg University Hospital, Strasbourg, France.
Nicolas MeyerDepartment of Biostatistics, Strasbourg University Hospital, France.
Pierre DiemunschDepartment of Anesthesiology and Intensive Care, Hautepierre Hospital, Strasbourg University Hospital, France; Institut Hospitalo-Universitaire "Image-Guided Surgery", Strasbourg University Hospital, Strasbourg, France; Equipe d'Accueil 3072, Medical School, Strasbourg University, Strasbourg, France.
Hôpitaux Universitaires de Strasbourg · FRHôpital Civil, Strasbourg · FRInstitut de Recherche contre les Cancers de l’Appareil Digestif · FRStony Brook Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGround-glass opacities are the most frequent radiologic features of COVID-19 patients. We aimed to determine the feasibility of automated lung volume measurements, including ground-glass volumes, on the CT of suspected COVID-19 patients. Our goal was to create an automated and quantitative measure of ground-glass opacities from lung CT images that could be used clinically for diagnosis, triage and research.

designSingle centre, retrospective, observational study. MEASUREMENTS: Demographic data, respiratory support treatment (synthetised in the maximal respiratory severity score) and CT-images were collected. Volume of abnormal lung parenchyma was measured with conventional semi-automatic software and with a novel automated algorithm based on voxels X-Ray attenuation. We looked for the relationship between the automated and semi-automated evaluations. The association between the ground-glass opacities volume and the maximal respiratory severity score was assessed. MAIN

resultsThirty-seven patients were included in the main outcome analysis. The mean duration of automated and semi-automated volume measurement process were 15 (2) and 93 (41) min, respectively (p=8.05*10

conclusionThe feasibility and preliminary validity of automated impaired lung volume measurements in a high-density COVID-19 cluster was confirmed by our results.

Indexed as

AlgorithmsAutomationCOVID-19Feasibility StudiesFemaleHumansLungLung Volume MeasurementsMaleMiddle AgedReproducibility of ResultsRetrospective StudiesSeverity of Illness IndexSoftwareSupine PositionTime FactorsARDSCOVID-19CT-scanInfectious diseaseSeverity assessmentTriage

Identifiers

PMID33197638
PMCPMC7664353
OpenAlexW3099588501

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.