Observational studyJournal of the American Geriatrics Society2021
Predicting In-Hospital Mortality in COVID-19 Older Patients with Specifically Developed Scores.
Observational study in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- One Score Fits All? A Narrative Review on Early Warning Scores for Older Adults in the Emergency Department in the Era of Personalized Medicine.Journal of personalized medicine · 2026Review
- Comparison of the performance of four clinical prediction rules for mortality in patients with COVID-19.PloS one · 2026Article
- Predictive accuracy of 4C Mortality Score and Acute Physiology and Chronic Health Evaluation scores for mortality in COVID-19 patients admitted to intensive care unit.World journal of critical care medicine · 2025Article
- Predictivity of the Prognostic Nutritional Index and Systemic Inflammation Index for All-Cause In-Hospital Mortality in Geriatric and Adult COVID-19 Inpatients.Journal of clinical medicine · 2024Article
- Predicting mortality risk in hospitalized COVID-19 patients: an early model utilizing clinical symptoms.BMC pulmonary medicine · 2024Article
- Association of Serum Krebs von den Lungen-6 (KL-6) Levels and Disease Severity in Patients Hospitalized with COVID-19.Infectious diseases & clinical microbiology · 2023Article
- Performance of point-of-care severity scores to predict prognosis in patients admitted through the emergency department with COVID-19.Journal of hospital medicine · 2023Article
- Mortality in COVID-19 older patients hospitalized in a geriatric ward: Is obesity protective?BMC geriatrics · 2023Article
- ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age.BMC geriatrics · 2023Observational
- Clinical and Laboratory Predictors of Mortality in Severe COVID-19 Pneumonia: A Retrospective Study from India.Thoracic research and practice · 2023Article
- Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID-19 patients.Aging medicine (Milton (N.S.W)) · 2023Article
- Utility of the 4C ISARIC mortality score in hospitalized COVID-19 patients at a large tertiary Saudi Arabian center.Multidisciplinary respiratory medicine · 2023Article
- Were metabolic and other chronic diseases the driven onset epidemic forces of COVID-19 in Mexico?Frontiers in public health · 2023Article
- One-on-one comparison between qCSI and NEWS scores for mortality risk assessment in patients with COVID-19.Annals of medicine · 2022Article
- Nutritional parameters associated with prognosis in non-critically ill hospitalized COVID-19 patients: The NUTRI-COVID19 study.Clinical nutrition (Edinburgh, Scotland) · 2022Article
- Older patients with COVID-19 and neuropsychiatric conditions: A study of risk factors for mortality.Brain and behavior · 2022Observational
- External Validation of COVID-19 Risk Scores during Three Waves of Pandemic in a German Cohort-A Retrospective Study.Journal of personalized medicine · 2022Article
- The Usefulness of the COVID-GRAM Score in Predicting the Outcomes of Study Population with COVID-19.International journal of environmental research and public health · 2022Article
- Long-Term Effects of Hospitalization for COVID-19 on Frailty and Quality of Life in Older Adults ≥80 Years.Journal of clinical medicine · 2022Article
- External validation of risk scores to predict in-hospital mortality in patients hospitalized due to coronavirus disease 2019.European journal of internal medicine · 2022Article
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesSeveral scoring systems have been specifically developed for risk stratification in COVID-19 patients.
designWe compared, in a cohort of confirmed COVID-19 older patients, three specifically developed scores with a previously established early warning score. Main endpoint was all causes in-hospital death.
settingThis is a single-center, retrospective observational study, conducted in the Emergency Department (ED) of an urban teaching hospital, referral center for COVID-19.
participantsWe reviewed the clinical records of the confirmed COVID-19 patients aged 60 years or more consecutively admitted to our ED over a 6-week period (March 1st to April 15th, 2020). A total of 210 patients, aged between 60 and 98 years were included in the study cohort. MEASUREMENTS: International Severe Acute Respiratory Infection Consortium Clinical Characterization Protocol-Coronavirus Clinical Characterization Consortium (ISARIC-4C) score, COVID-GRAM Critical Illness Risk Score (COVID-GRAM), quick COVID-19 Severity Index (qCSI), National Early Warning Score (NEWS).
resultsMedian age was 74 (67-82) and 133 (63.3%) were males. Globally, 42 patients (20.0%) deceased. All the score evaluated showed a fairly good predictive value with respect to in-hospital death. The ISARIC-4C score had the highest area under ROC curve (AUROC) 0.799 (0.738-0.851), followed by the COVID-GRAM 0.785 (0.723-0.838), NEWS 0.764 (0.700-0.819), and qCSI 0.749 (0.685-0.806). However, these differences were not statistical significant.
conclusionAmong the evaluated scores, the ISARIC-4C and the COVID-GRAM, calculated at ED admission, had the best performance, although the qCSI had similar efficacy by evaluating only three items. However, the NEWS, already widely validated in clinical practice, had a similar performance and could be appropriate for older patients with COVID-19.
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