Evidence map›Paper›PMID 33197079›Full record

SynthesisBritish journal of clinical pharmacology2021

A systematic literature review of LASA error interventions.

Rachel Bryan, Jeffrey K Aronson, Alison J Williams, Sue Jordan

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in British journal of clinical pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. A systematic literature review of LASA error interventions.British journal of clinical pharmacology · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rachel BryanCollege of Arts and Humanities, Swansea University, Swansea, UK.ORCID 0000-0001-8617-3882
Jeffrey K AronsonUniversity of Oxford, Oxford, UK.ORCID 0000-0003-1139-655X
Alison J WilliamsCollege of Arts and Humanities, Swansea University, Swansea, UK.
Sue JordanCollege of Arts and Humanities, Swansea University, Swansea, UK.
Swansea University · GBUniversity of Oxford · GB

Funding

Swansea University studentship
6 · The paper itself

Abstract

aimsThe aim of this systematic review was to explore and evaluate the efficacy of interventions to reduce the prevalence of look-alike, sound-alike (LASA) medication name errors.

methodsWe conducted a systematic review of the literature, searching PubMed, EMBASE, Scopus and Web of Science up to December 2016, and re-ran the search in February 2020 for later results. We included studies of interventions to reduce LASA errors and included randomized controlled trials, controlled before-and-after studies, and interrupted time series. Details were registered in Prospero (ID: CRD42016048198).

resultsWe identified six studies that fulfilled our inclusion criteria. All were conducted in laboratories. Given the diversity in the included studies, we did not conduct a meta-analysis and instead report the findings narratively. The only intervention explored in RCTs was capitalization of selected letters ("Tall Man"), for which we found limited efficacy and no consensus.

conclusionsTall Man lettering is a marginally effective intervention to reduce LASA errors, with a number of caveats. We suggest that Tall Man gives rise to a "quasi-placebo effect", whereby a user derives more benefit from Tall Man lettering if they are aware of its purpose.

Indexed as

Medication ErrorsConsensusHumansInterrupted Time Series AnalysisMaleconfusion errorsdrug nomenclaturelook-alikename confusion(on scholar one).sound-alike

Identifiers

PMID33197079
PMCPMC9328434
OpenAlexW3101245758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.