Evidence map›Paper›PMID 33196687›Full record

ArticlePloS one2020

A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model.

Andrew R Plummer, Jonathan L du Bois, Joseph M Flynn, Jens Roesner, Siu Man Lee, Patrick Magee, Malcolm Thornton, Andrew Padkin, Harinderjit S Gill

Abstract readValidation Study
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. The COVID-19 pandemic: a gateway between one world and the next!Anaesthesia, critical care & pain medicine · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew R PlummerDepartment of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
Jonathan L du BoisDepartment of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
Joseph M FlynnDepartment of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
Jens RoesnerDepartment of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
Siu Man LeeRoyal United Hospitals NHS Foundation Trust, Bath, North Somerset, United Kingdom.ORCID 0000-0002-2553-0986
Patrick MageeBMI Bath Clinic, Bath, North Somerset, United Kingdom.
Malcolm ThorntonRoyal United Hospitals NHS Foundation Trust, Bath, North Somerset, United Kingdom.
Andrew PadkinRoyal United Hospitals NHS Foundation Trust, Bath, North Somerset, United Kingdom.
Harinderjit S GillDepartment of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.ORCID 0000-0002-7740-2062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith large numbers of COVID-19 patients requiring mechanical ventilation and ventilators possibly being in short supply, in extremis two patients may have to share one ventilator. Careful matching of patient ventilation requirements is necessary. However, good matching is difficult to achieve as lung characteristics can have a wide range and may vary over time. Adding flow restriction to the flow path between ventilator and patient gives the opportunity to control the airway pressure and hence flow and volume individually for each patient. This study aimed to create and validate a simple model for calculating required flow restriction. METHODS AND

findingsWe created a simple linear resistance-compliance model, termed the BathRC model, of the ventilator tubing system and lung allowing direct calculation of the relationships between pressures, volumes, and required flow restriction. Experimental measurements were made for parameter determination and validation using a clinical ventilator connected to two test lungs. For validation, differing amounts of restriction were introduced into the ventilator circuit. The BathRC model was able to predict tidal lung volumes with a mean error of 4% (min:1.2%, max:9.3%).

conclusionWe present a simple model validated model that can be used to estimate required flow restriction for dual patient ventilation. The BathRC model is freely available; this tool is provided to demonstrate that flow restriction can be readily estimated. Models and data are available at DOI 10.15125/BATH-00816.

Indexed as

Ventilators, MechanicalBetacoronavirusCoronavirus InfectionsCOVID-19Equipment DesignHumansLinear ModelsPandemicsPneumonia, ViralPressureRespiration, ArtificialSARS-CoV-2Tidal Volume

Identifiers

PMID33196687
PMCPMC7668571

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.