ArticlePloS one2020
Incidence of hospitalization and mortality due to stroke in young adults, residents of developed regions in Brazil, 2008-2018.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 20 citations in OpenAlex.
- Proportional Stroke Mortality in Espírito Santo, Brazil: A 20-Year Joinpoint Regression Study.Epidemiologia (Basel, Switzerland) · 2025Article
- Stroke Deaths Profile and Its Subtypes in Brazil: Analysis Using Machine Learning.Global heart · 2025Article
- Economic burden, mortality, and incidence of hospital admissions for cerebrovascular diseases in Brazil from 2017 to 2022: a perspective of the Brazilian Unified Health System.Revista de saude publica · 2025Article
- Mortality outcomes in 35,433 patients admitted for acute haemorrhagic stroke in Australia: A population-linkage study.International journal of cardiology. Cardiovascular risk and prevention · 2024Article
- Early neonatal mortality trend in adolescent pregnant women in the State of São Paulo, Brazil, from 1996 to 2017.Translational pediatrics · 2021Article
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8 authors at 4 institutions in 2 countries.
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Abstract
introductionWe evaluated trends in hospitalization incidence and mortality due to hemorrhagic and ischemic stroke in young adults, according to gender and developed regions in Brazil.
methodsBetween 2008-2018, we performed a population-based time-series study using official hospitalization and death data due to stroke, in individuals aged 10-49 years, from Southeast and South, Brazil. Data were based on reports from the Unified Health System of Hospital Information System and Mortality Information System. Stroke was defined by the International Classification of Diseases, 10th revision (I60-I63). A Prais-Winsten regression model was performed and the Annual Percentage Change was calculated.
resultsIn total, 78,123 hospitalizations of individuals aged 10-49 years were recorded, of which 59,448 (76%) resulted from hemorrhagic stroke (HS). The hospitalizations for HS was significantly decreased (- 4.37%) among men and women in both regions. The hospitalizations for ischemic stroke (IS) was flat, except between 2011 and 2018, when IS hospitalization rates increased. In the analysis by states, HS hospitalizations declined across all states, except for Espírito Santo, where it remained unchanged (p > 0.05). IS flat hospitalizations were observed in all states, except Espírito Santo, where it increased by 24.93%. In terms of mortality, 28,625 deaths were recorded, of which 26,548 (92.7%) resulted from HS. HS mortality decreased significantly by -3.48%and IS mortality by -3.84%. Decreases also occurred in all Southeast and South states (p < 0.05). IS remained unchanged across all states, except Minas Gerais, where it decreased by -14.95%.
conclusionsWe identified a decline in the hospitalizations and mortality of HS and a flat trend for IS in developed regions of Brazil. The recent period (2011-2018) demonstrated increasing rates in the hospitalizations of IS in both regions and genders. The mortality rates for HS and IS decreased between 2008-2018 in Southeast and South Brazil for both genders.
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