Evidence map›Paper›PMID 33196555›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2021

COVID-19 Related Medical Mistrust, Health Impacts, and Potential Vaccine Hesitancy Among Black Americans Living With HIV.

Laura M Bogart, Bisola O Ojikutu, Keshav Tyagi, David J Klein, Matt G Mutchler, Lu Dong, Sean J Lawrence, Damone R Thomas, Sarah Kellman

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05582746 (Localized mHealth Approach to Boosting COVID-19 Testing and Vaccine Literacy, Access, and Uptake Among Women With Criminal Legal System Involvement), which is not on this map. Cited by 295 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
295citing papers in PubMed, 8 pooled it
41.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05582746 nacompletednot on this mapstarted 2022, after this paper: background citation

Localized mHealth Approach to Boosting COVID-19 Testing and Vaccine Literacy, Access, and Uptake Among Women With Criminal Legal System Involvement

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2022 to 2024Enrolled295ConditionsCOVID-19 PandemicArmsTri-City COVID Attitudes Study
3 · Its place in the literature

Who cites it

295 citing papers in PubMed, 8 syntheses or guidelines pooled it, 484 citations in OpenAlex.

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235 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Laura M BogartRAND Corporation.
Bisola O OjikutuDivision of Infectious Diseases, Brigham and Women's Hospital, Boston, MA.
Keshav TyagiCommunity-Based Research, APLA Health & Wellness; and.
David J KleinRAND Corporation.
Matt G MutchlerCommunity-Based Research, APLA Health & Wellness; and.
Lu DongRAND Corporation.
Sean J LawrenceCommunity-Based Research, APLA Health & Wellness; and.
Damone R ThomasCommunity-Based Research, APLA Health & Wellness; and.
Sarah KellmanCommunity-Based Research, APLA Health & Wellness; and.
APLA Health · USRAND Corporation · USMassachusetts General Hospital · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Still Climbin': A Randomized Controlled Trial of an Intervention to Improve Coping with Discrimination, Address Medical Mistrust, and Reduce Health Disparities among Black Sexual Minority MenR01MD014722 · NIMHD · RAND CORPORATION · PI BOGART, LAURA M · 2020 to 2025
$3.6M
A Randomized Controlled Trial of an Antiretroviral Treatment Adherence Intervention for HIV+ African AmericansR01NR017334 · NINR · RAND CORPORATION · PI BOGART, LAURA M · 2017 to 2021
$3.1M
NIAID NIH HHS P30 AI060354NIMHD NIH HHS R01 MD014722NIMH NIH HHS P30 MH058107NIMH NIH HHS R25 MH067127NINR NIH HHS R01 NR017334
6 · The paper itself

Abstract

backgroundMedical mistrust, a result of systemic racism, is prevalent among Black Americans and may play a role in COVID-19 inequities. In a convenience sample of HIV-positive Black Americans, we examined associations of COVID-19-related medical mistrust with COVID-19 vaccine and COVID-19 treatment hesitancy and negative impacts of COVID-19 on antiretroviral therapy (ART) adherence.

methodsParticipants were 101 HIV-positive Black Americans (age: M = 50.3 years; SD = 11.5; 86% cisgender men; 77% sexual minority) enrolled in a randomized controlled trial of a community-based ART adherence intervention in Los Angeles County, CA. From May to July 2020, participants completed telephone interviews on negative COVID-19 impacts, general COVID-19 mistrust (eg, about the government withholding information), COVID-19 vaccine and treatment hesitancy, and trust in COVID-19 information sources. Adherence was monitored electronically with the Medication Event Monitoring System.

resultsNearly all participants (97%) endorsed at least one general COVID-19 mistrust belief, and more than half endorsed at least one COVID-19 vaccine or treatment hesitancy belief. Social service and health care providers were the most trusted sources. Greater COVID-19 mistrust was related to greater vaccine and treatment hesitancy [b (SE) = 0.85 (0.14), P < 0.0001 and b (SE) = 0.88 (0.14), P < 0.0001, respectively]. Participants experiencing more negative COVID-19 impacts showed lower ART adherence, assessed among a subset of 49 participants [b (SE) = -5.19 (2.08), P = 0.02]. DISCUSSION: To prevent widening health inequities, health care providers should engage with communities to tailor strategies to overcome mistrust and deliver evidence-based information, to encourage COVID-19 vaccine and treatment uptake.

Indexed as

COVID-19 VaccinesAdultAnti-Retroviral AgentsBlack or African AmericanCOVID-19COVID-19 Drug TreatmentDrug MonitoringFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansLos AngelesMaleMedication AdherenceMiddle AgedSARS-CoV-2Anti-Retroviral AgentsCOVID-19 Vaccines

Identifiers

PMID33196555
PMCPMC7808278
OpenAlexW3102988078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.