Evidence map›Paper›PMID 33196549›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2021

Role of Social Networks and Social Norms in Future PrEP Use in a Racially Diverse Sample of At-Risk Women and Members of Their Social Networks.

Laura M Johnson, Harold D Green, Brandon Koch, Jamila K Stockman, Marisa Felsher, Alexis M Roth, Karla D Wagner

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura M JohnsonSchool of Community Health Sciences, University of Nevada, Reno, NV.
Harold D GreenDepartment of Applied Health Science, Indiana School of Public Health, Indiana University, Bloomington, IN.
Brandon KochSchool of Community Health Sciences, University of Nevada, Reno, NV.
Jamila K StockmanDepartment of Medicine, School of Medicine, University of California, San Diego, San Diego, CA.
Marisa FelsherDivision of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MA; and.
Alexis M RothDepartment of Community Health & Prevention, Dornsife School of Public Health, Drexel University, Philadelphia, PA.
Karla D WagnerSchool of Community Health Sciences, University of Nevada, Reno, NV.

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
Networks and normative influences on sex and drug-related HIV risk in black womenR01DA038185 · NIDA · UNIVERSITY OF NEVADA RENO · PI WAGNER, KARLA D. · 2015 to 2019
$2.0M
Sex/Drug Tourism at the US/Mexico Border: Social Network Influences on HIV Risk.K01DA031031 · NIDA · UNIVERSITY OF NEVADA RENO · PI WAGNER, KARLA D. · 2010 to 2014
$882k
Packaging Pre-Exposure Prophylaxis (PrEP) to Prevent HIV Transmission among Women who Inject DrugsR21DA043417 · NIDA · DREXEL UNIVERSITY · PI ROTH, ALEXIS MARIE · 2017 to 2018
$442k
NCATS NIH HHS UL1 TR001442NIAID NIH HHS P30 AI036214NIDA NIH HHS K01 DA031031NIDA NIH HHS R01 DA038185NIDA NIH HHS R21 DA043417
6 · The paper itself

Abstract

objectiveDespite the efficacy of pre-exposure prophylaxis (PrEP) in reducing the risk of HIV infection, uptake remains low among many who are most vulnerable to HIV, such as Black and Latinx women. Interventions that target social networks to encourage at-risk women to initiate PrEP are underused.

designThis study used an egocentric network design and sampled Black/African American and Latinx women at risk of HIV as well as people from their social networks (N = 211) in a small, western city.

methodsMultivariable generalized linear mixed effects regression models investigated individual-level and network-level characteristics associated with likely future PrEP use.

resultsPrEP awareness was low, but once informed, 36% considered themselves likely to take it in the future. Perceived risk of HIV, perceived barriers to HIV testing, and participation in a 12-step program increased odds of anticipated PrEP use. A higher proportion of friends in one's network decreased odds of future PrEP use, whereas a higher proportion of network members who tested regularly for HIV increased odds of future PrEP use. A marginally significant interaction was detected between proportion of friends in one's network and proportion of the network perceived to test for HIV regularly (ie, testing norms). When HIV testing norms were low, a higher proportion of friends in the network decreased odds of likely PrEP use. However, this effect was reversed in contexts with strong testing norms.

conclusionWomen who are interested in PrEP may be embedded within social and normative contexts that can foster or inhibit PrEP uptake.

Indexed as

HIV-1Pre-Exposure ProphylaxisSocial NormsSocial SupportAdultAnti-HIV AgentsFemaleHIV InfectionsHumansMiddle AgedRacial GroupsRisk FactorsYoung AdultAnti-HIV Agents

Identifiers

PMID33196549
PMCPMC9276301

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.