Evidence map›Paper›PMID 33196343›Full record

ArticleJournal of the American Heart Association2020

Impact of Coronavirus Disease 2019 (COVID-19) on Patients With Congenital Heart Disease Across the Lifespan: The Experience of an Academic Congenital Heart Disease Center in New York City.

Matthew J Lewis, Brett R Anderson, Michael Fremed, Melissa Argenio, Usha Krishnan, Rachel Weller, Stéphanie Levasseur, Robert Sommer, Irene D Lytrivi, Emile A Bacha and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Remdesivir in COVID-19: pros and cons.Frontiers in pharmacology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Arrhythmia and COVID-19 in children.Clinical and experimental pediatrics · 2023
    Article
  9. Article
  10. Article
  11. COVID-19 in congenital heart disease patients: what did we learn?!Frontiers in cardiovascular medicine · 2023
    Article
  12. COVID-19 in Cyanotic Congenital Heart Disease.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Matthew J LewisDepartment of Medicine Columbia University Irving Medical Center New York NY.
Brett R AndersonDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Michael FremedDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Melissa ArgenioDepartment of Medicine Columbia University Irving Medical Center New York NY.
Usha KrishnanDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Rachel WellerDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Stéphanie LevasseurDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Robert SommerDepartment of Medicine Columbia University Irving Medical Center New York NY.
Irene D LytriviDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Emile A BachaDivision of Cardiothoracic Surgery Columbia University Irving Medical Center New York NY.
Julie VincentDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Wendy K ChungDepartment of Medicine Columbia University Irving Medical Center New York NY.
Erika B RosenzweigDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Thomas J StarcDepartment of Pediatrics Columbia University Irving Medical Center New York NY.
Marlon RosenbaumDepartment of Medicine Columbia University Irving Medical Center New York NY.
CUIMC Pediatric/Adult Congenital Heart Research Collaborative ‡
Columbia University Irving Medical Center · US

Funding

The Association of Damaging Genetic Variation With Ventricular Function in Hypoplastic Left Heart SyndromeK23HL143136 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LEWIS, MATTHEW · 2018 to 2022
$907k
NHLBI NIH HHS K23 HL143136
6 · The paper itself

Abstract

Background We sought to assess the impact and predictors of coronavirus disease 2019 (COVID-19) infection and severity in a cohort of patients with congenital heart disease (CHD) at a large CHD center in New York City. Methods and Results We performed a retrospective review of all individuals with CHD followed at Columbia University Irving Medical Center who were diagnosed with COVID-19 between March 1, 2020 and July 1, 2020. The primary end point was moderate/severe response to COVID-19 infection defined as (1) death during COVID-19 infection; or (2) need for hospitalization and/or respiratory support secondary to COVID-19 infection. Among 53 COVID-19-positive patients with CHD, 10 (19%) were <18 years of age (median age 34 years of age). Thirty-one (58%) had complex congenital anatomy including 10 (19%) with a Fontan repair. Eight (15%) had a genetic syndrome, 6 (11%) had pulmonary hypertension, and 9 (17%) were obese. Among adults, 18 (41%) were physiologic class C or D. For the entire cohort, 9 (17%) had a moderate/severe infection, including 3 deaths (6%). After correcting for multiple comparisons, the presence of a genetic syndrome (odds ratio [OR], 35.82;

Indexed as

Academic Medical CentersAdultAgedAzithromycinCohort StudiesCOVID-19FemaleGenetic Diseases, InbornHeart Defects, CongenitalHospitalizationHumansHydroxychloroquineIntubation, IntratrachealMaleNew York CityOxygen Inhalation TherapyAzithromycinHydroxychloroquineadult congenital heart diseasecongenital heart diseaseCOVID‐19outcomes

Identifiers

PMID33196343
PMCPMC7763774
OpenAlexW3106024344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.