ArticleCirculation2020
Lysyl Oxidase Inhibition Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in Mice.
Abstract readLetter
In one paragraph
Article in Circulation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- The aorta in Marfan syndrome: from molecular mechanisms to mechanobiological dysfunction.Cardiovascular research · 2026Review
- Lack of endothelial estrogen receptor alpha signaling exacerbates abdominal aortic aneurysm in male mice.American journal of physiology. Heart and circulatory physiology · 2026Article
- Dual-Emission Fluorescent Probe for Simultaneous Visualization of Monoamine Oxidase A and Lysyl Oxidase in Alzheimer's Disease Cell Models.Chemical & biomedical imaging · 2026Article
- Emerging Mechanisms of Abdominal Aortic Aneurysm.Current atherosclerosis reports · 2026Review
- Sexual Dimorphism in Abdominal Aortic Aneurysm-Insights from Clinical and Experimental Studies.Journal of vascular diseases · 2025Article
- Unleashing PD-1: a duel of immunity in aortic aneurysm formation.The Journal of clinical investigation · 2024Article
- Effects of Age, Sex, and Extracellular Matrix Integrity on Aortic Dilatation and Rupture in a Mouse Model of Marfan Syndrome.Arteriosclerosis, thrombosis, and vascular biology · 2023Article
- Novel pharmacological approaches in abdominal aortic aneurysm.Clinical science (London, England : 1979) · 2023Review
- Treatment With Small Molecule Inhibitors of Advanced Glycation End-Products Formation and Advanced Glycation End-Products-Mediated Collagen Cross-Linking Promotes Experimental Aortic Aneurysm Progression in Diabetic Mice.Journal of the American Heart Association · 2023Article
- Celastrol Supplementation Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in Mice.Biomolecules · 2023Article
- Ciprofloxacin exacerbates dysfunction of smooth muscle cells in a microphysiological model of thoracic aortic aneurysm.JCI insight · 2023Article
- Targeting lysyl-oxidase (LOX) may facilitate intramural periarterial drainage for the treatment of Alzheimer's disease.Cerebral circulation - cognition and behavior · 2023Review
- Mechanical and matrix effects of short and long-duration exposure to beta-aminopropionitrile in elastase-induced model abdominal aortic aneurysm in mice.JVS-vascular science · 2023Article
- Critical involvement of lysyl oxidase in seizure-induced neuronal damage through ERK-Alox5-dependent ferroptosis and its therapeutic implications.Acta pharmaceutica Sinica. B · 2022Article
- Effect of Anti-Hypertensive Medication on Plasma Concentrations of Lysyl Oxidase: Evidence for Aldosterone-IL-6-Dependent Regulation of Lysyl Oxidase Blood Concentration.Biomedicines · 2022Article
- Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition.Scientific reports · 2022Article
- Endothelial NCK2 promotes atherosclerosis progression in male but not femaleFrontiers in cardiovascular medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Michihiro Okuyama *Saha Cardiovascular Research Center (M.O., W.J., A.J., J.Z.C., D.A.H., L.Y., V.S.), University of Kentucky, Lexington.
Weihua Jiang *Saha Cardiovascular Research Center (M.O., W.J., A.J., J.Z.C., D.A.H., L.Y., V.S.), University of Kentucky, Lexington.
Aida Javidan *Saha Cardiovascular Research Center (M.O., W.J., A.J., J.Z.C., D.A.H., L.Y., V.S.), University of Kentucky, Lexington.
Jeff Zheying Chen *Saha Cardiovascular Research Center (M.O., W.J., A.J., J.Z.C., D.A.H., L.Y., V.S.), University of Kentucky, Lexington.
Deborah A HowattSaha Cardiovascular Research Center (M.O., W.J., A.J., J.Z.C., D.A.H., L.Y., V.S.), University of Kentucky, Lexington.
Lihua YangSaha Cardiovascular Research Center (M.O., W.J., A.J., J.Z.C., D.A.H., L.Y., V.S.), University of Kentucky, Lexington.
Mika HamaguchiDepartment of Cardiology, Pulmonology, Hypertension, and Nephrology (M.H., J.A.), Ehime University Graduate School of Medicine, Toon, Japan.
Takumi YasugiDepartment of Cardiovascular and Thoracic Surgery (T.Y.), Ehime University Graduate School of Medicine, Toon, Japan.
Jun AonoDepartment of Cardiology, Pulmonology, Hypertension, and Nephrology (M.H., J.A.), Ehime University Graduate School of Medicine, Toon, Japan.
Roberto Irenardo Vazquez-PadronDepartment of Surgery, Division of Vascular Surgery, University of Miami, FL (R.I.V.-P.).
Venkateswaran SubramanianSaha Cardiovascular Research Center (M.O., W.J., A.J., J.Z.C., D.A.H., L.Y., V.S.), University of Kentucky, Lexington.
Funding
The role of IKKß in linking obesity to adipose tissue inflammation and adipogeneP20GM103527 · NIGMS · UNIVERSITY OF KENTUCKY · PI MORRIS, ANDREW J · 2012 to 2017
$13.7MPilot Projects ProgramP30GM127211 · NIGMS · UNIVERSITY OF KENTUCKY · PI CASSIS, LISA A · 2018 to 2022
$5.7MAdventitial-medial interactions in thoracic aortic diseasesR01HL133723 · NHLBI · UNIVERSITY OF KENTUCKY · PI DAUGHERTY, ALAN · 2016 to 2019
$2.9MCalpains and Abdominal Aortic AneurysmsR01HL130086 · NHLBI · UNIVERSITY OF KENTUCKY · PI SUBRAMANIAN, VENKATESWARAN · 2017 to 2020
$1.9MNHLBI NIH HHS R01 HL130086NHLBI NIH HHS R01 HL133723NIGMS NIH HHS P20 GM103527NIGMS NIH HHS P30 GM127211
Abstract
PubMed holds no abstract for this paper.
Indexed as
Aortic Aneurysm, AbdominalSex CharacteristicsAnimalsEnzyme InhibitorsExtracellular Matrix ProteinsFemaleHumansMaleMiceProtein-Lysine 6-OxidaseEnzyme InhibitorsExtracellular Matrix ProteinsLox protein, mouseProtein-Lysine 6-Oxidaseaminopropionitrileangiotensin IIaortic aneurysm, abdominalprotein-lysine 6-oxidasesex characteristics
Identifiers
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Textmetadata
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.