Evidence map›Paper›PMID 33196059›Full record

ArticleCancer medicine journal2020

Hepatectomy for Breast Cancer Metastasis and Sarcoma are more likely to have Adverse Outcomes than Hepatectomy for Primary Hepatocellular Cancer or for Colorectal Metastasis.

Hassan Aziz, Kamil Hanna, Muhammad Wasif Saif, Muhammad Ameen Rauf, Yuri Genyk, Mohd Raashid Sheikh

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hassan AzizDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Kamil HannaWestchester Medical Center, Valhalla, NY, USA.
Muhammad Wasif SaifNorthwell Health Cancer Institute, Zucker School of Medicine and Feinstein Institutes of Research, Manhasset, NY, USA.
Muhammad Ameen RaufVanderbilt University Medical Center, Nashville, Tennessee, USA.
Yuri GenykDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Mohd Raashid SheikhDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
University of Southern California · USVanderbilt University Medical Center · USWestchester Medical Center · US

Funding

Northwell Health NCORPUG1CA189850 · NCI · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI VINCENT P VINCIGUERRA · 2014 to 2026
$13.3M
NCI NIH HHS UG1 CA189850
6 · The paper itself

Abstract

introductionOutcomes for hepatectomy for breast cancer metastasis and sarcomatous disease processes are not well defined in literature. We sought to use a national database to identify outcomes in these patients compared to subset of patients more well studied in literature - primary Hepatocellular cancer patients and patients with colorectal metastasis.

methodsWe identified patients undergoing major hepatectomy (≥ 3 segments) for primary hepatocellular cancer (HCC), sarcoma metastasis, breast cancer metastasis, and colorectal metastasis using NSQIP database. The Primary outcome measure was 30-day mortality. Secondary outcome measures were 30-day readmission and complication rates.

resultsA total of 5580 patients underwent major hepatectomy during the study period. Patients who underwent hepatectomy for breast cancer metastasis had higher incidence of in-hospital complications (37%) compared to sarcoma (29%), colon (26%), and HCC patients (24%) and 30-days readmission rate (37%

conclusionPatients undergoing major hepatectomies for breast cancer metastasis and sarcoma are more likely to have adverse outcomes than compared to their counterparts. This difference highlights the lack of experience in managing breast cancer and sarcoma with metastatic disease to the liver. This also highlights the difference in tumor biology among all the lesions we studied. An extensive discussion should take place when dealing with breast and sarcoma lesions in the liver because of these outcomes.

Indexed as

Breast cancerColorectal cancerHepatectomyMetastasisPrimary hepatocellular cancerSarcoma

Identifiers

PMID33196059
PMCPMC7664114
OpenAlexW3098551603

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.