Evidence map›Paper›PMID 33195913›Full record

ArticleACS omega2020

New Bifunctional Chelator 3p-

Xiang Sun, Chi Soo Kang, Inseok Sin, Shuyuan Zhang, Siyuan Ren, Haixing Wang, Dijie Liu, Michael R Lewis, Hyun-Soon Chong

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. New Radiopharmaceutical Tracers in Breast Cancer Diagnosis and Therapy.Anti-cancer agents in medicinal chemistry · 2025
    Review
  5. Radiochemical and Biological Evaluation of 3p-Pharmaceuticals (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiang SunDepartment of Chemistry, Lewis College of Science and Letters, Illinois Institute of Technology, Chicago, Illinois 60616, United States.
Chi Soo KangDepartment of Chemistry, Lewis College of Science and Letters, Illinois Institute of Technology, Chicago, Illinois 60616, United States.
Inseok SinDepartment of Chemistry, Lewis College of Science and Letters, Illinois Institute of Technology, Chicago, Illinois 60616, United States.
Shuyuan ZhangDepartment of Chemistry, Lewis College of Science and Letters, Illinois Institute of Technology, Chicago, Illinois 60616, United States.
Siyuan RenDepartment of Chemistry, Lewis College of Science and Letters, Illinois Institute of Technology, Chicago, Illinois 60616, United States.
Haixing WangDepartment of Chemistry, Lewis College of Science and Letters, Illinois Institute of Technology, Chicago, Illinois 60616, United States.
Dijie LiuDepartment of Veterinary Medicine and Surgery, University of Missouri-Columbia, Columbia, Missouri 65211, United States.
Michael R LewisDepartment of Veterinary Medicine and Surgery, University of Missouri-Columbia, Columbia, Missouri 65211, United States.
Hyun-Soon ChongDepartment of Chemistry, Lewis College of Science and Letters, Illinois Institute of Technology, Chicago, Illinois 60616, United States.
Illinois Institute of Technology · USUniversity of Missouri · US

Funding

New Bifunctional Ligands for RadioimmunotherapyR01CA112503 · NCI · ILLINOIS INSTITUTE OF TECHNOLOGY · PI CHONG, HYUN-SOON · 2006 to 2017
$2.0M
NCI NIH HHS R01 CA112503
6 · The paper itself

Abstract

We have developed structurally unique bifunctional chelators in the NETA, NE3TA, and DEPA series for potential radiopharmaceutical applications. As part of our continued research efforts to generate efficient bifunctional chelators for targeted radionuclide therapy and imaging of various diseases, we designed a scorpion-like chelator that is proposed to completely saturate the coordination spheres of Y(III) and Lu(III). We herein report the synthesis and evaluation of a new chelator (3p-

Identifiers

PMID33195913
PMCPMC7658932
OpenAlexW3097220104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.