Evidence map›Paper›PMID 33195875›Full record

ArticleExposure and health2020

Arsenic exposure in relation to apple consumption among infants in the New Hampshire Birth Cohort Study.

A J Signes-Pastor, T Punshon, K L Cottingham, B P Jackson, V Sayarath, D Gilbert-Diamond, S Korrick, M R Karagas

Open access · greenAbstract read
In one paragraph

Article in Exposure and health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

A J Signes-PastorChildren's Environmental Health and Disease Prevention Research Center, Dartmouth College, Hanover, NH, 03755.
T PunshonChildren's Environmental Health and Disease Prevention Research Center, Dartmouth College, Hanover, NH, 03755.
K L CottinghamChildren's Environmental Health and Disease Prevention Research Center, Dartmouth College, Hanover, NH, 03755.
B P JacksonChildren's Environmental Health and Disease Prevention Research Center, Dartmouth College, Hanover, NH, 03755.
V SayarathChildren's Environmental Health and Disease Prevention Research Center, Dartmouth College, Hanover, NH, 03755.
D Gilbert-DiamondChildren's Environmental Health and Disease Prevention Research Center, Dartmouth College, Hanover, NH, 03755.
S KorrickDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115.
M R KaragasChildren's Environmental Health and Disease Prevention Research Center, Dartmouth College, Hanover, NH, 03755.
Dartmouth College · USHarvard University · US

Funding

VARIATION IN BIOACCUMULATION AND BIOMAGNIFICATION OF METALS IN NORTHERN US LAKESP42ES007373 · NIEHS · DARTMOUTH COLLEGE · PI STANTON, BRUCE A. · 1995 to 2019
$52.0M
A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
Relation Between In-utero Vitamin D and Immune Function in Early Childhood P20GM104416 · NIGMS · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA · 2013 to 2022
$23.7M
Project 3: Placental Biomarkers of Exposure and Outcome (Marsit)P01ES022832 · NIEHS · DARTMOUTH COLLEGE · PI MURRAY, CAROLYN J · 2013 to 2018
$4.7M
Training Program for Quantitative Population Sciences in CancerR25CA134286 · NCI · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA, TOSTESON, TOR D · 2009 to 2018
$3.0M
NCI NIH HHS R25 CA134286NIEHS NIH HHS P01 ES022832NIEHS NIH HHS P42 ES007373NIGMS NIH HHS P20 GM104416NIH HHS UH3 OD023275
6 · The paper itself

Abstract

Infants and young children commonly consume apple-based products, which may contain high concentrations of inorganic arsenic (iAs). As yet, iAs exposure from ingesting apple products has not been well-characterized in early childhood. Therefore, we investigated the association between urinary arsenic concentrations and intake of apple products in one-year-old infants participating in the New Hampshire Birth Cohort Study. A three-day food diary prior to collection of a spot urine sample was used to determine infant's consumption of apple products. The sum of urinary iAs, monomethylarsonic acid, and dimethylarsinic acid, referred to as ΣAs, was used to estimate iAs exposure. A total of 242 infants had urinary arsenic speciation analyzed without indication of fish/seafood consumption (urinary arsenobetaine < 1 μg/L) and with a completed three-day food diary. Of these, 183 (76%) infants ate apples or products containing apple. The geometric mean urinary ΣAs among the 59 infants who did not consume any type of apple product was 2.78 μg/L as compared to 2.38, 2.46, 2.28, and 2.73 μg/L among infants who exclusively consumed apple juice (

Identifiers

PMID33195875
PMCPMC7665059
OpenAlexW3016099865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.