Evidence map›Paper›PMID 33195478›Full record

ArticleFrontiers in cardiovascular medicine2020

Late-Stage Löffler's Endocarditis Mimicking Cardiac Tumor: A Case Report.

Takafumi Koyama, Hiroyuki Yamamoto, Manabu Matsumoto, Jun Isogai, Tadashi Isomura, Shinji Tanaka

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in cardiovascular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Takafumi KoyamaDepartment of Cardiology, Shonan Fujisawa Tokushukai Hospital, Kanagawa, Japan.
Hiroyuki YamamotoDepartment of Cardiovascular Medicine, Narita-Tomisato Tokushukai Hospital, Chiba, Japan.
Manabu MatsumotoDepartment of Pathology, National Cerebral and Cardiovascular Center, Suita, Japan.
Jun IsogaiDepartment of Radiology, Asahi General Hospital, Asahi, Japan.
Tadashi IsomuraDepartment of Cardiovascular Surgery, IMS Katsushika Heart Center, Tokyo, Japan.
Shinji TanakaDepartment of Cardiology, Shonan Fujisawa Tokushukai Hospital, Kanagawa, Japan.
Yokufukai Hospital · JPAsahi Hospital · JPKatsushika Medical Center · JPNational Cerebral and Cardiovascular Center · JPSuita Tokushukai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Löffler's endocarditis (cardiac involvement in hypereosinophilic syndrome) is rare yet life-threatening if left untreated. We describe a case of hypereosinophilic syndrome presenting as a cardiac mass with an abnormal electrocardiogram. Diagnostic studies of the cardiac mass strongly suggested a malignant cardiac tumor invading the papillary muscle. Thus, excision of the cardiac mass and endomyocardial resection with mitral valve replacement were successfully performed. Pathology revealed various stages of thrombosis and irreversible myocardial damage caused by eosinophilic infiltration with no malignancy, leading to the correct diagnosis of late-stage Löffler's endocarditis. The subsequent combination of anticoagulation and corticosteroids was effective with a favorable outcome. This case highlights pitfalls in multimodality imaging of cardiac thrombus and the clinical significance of considering Löffler's endocarditis in the diagnostic work-up of a cardiac mass.

Indexed as

cardiac magnetic resonancecardiac thrombusendomyocardial fibrosishypereosinophilic syndromeLöffler's endocarditis

Identifiers

PMID33195478
PMCPMC7658372
OpenAlexW3095682852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.