Evidence map›Paper›PMID 33195341›Full record

ArticleFrontiers in medicine2020

Antigen-Specific Immunoadsorption With the Glycosorb® ABO Immunoadsorption System as a Novel Treatment Modality in Pure Red Cell Aplasia Following Major and Bidirectional ABO-Incompatible Allogeneic Hematopoietic Stem Cell Transplantation.

Ammon Handisurya, Nina Worel, Werner Rabitsch, Marija Bojic, Sahra Pajenda, Roman Reindl-Schwaighofer, Wolfgang Winnicki, Andreas Vychytil, Hanna A Knaus, Rainer Oberbauer and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ammon HandisuryaDepartment of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Nina WorelDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Vienna, Austria.
Werner RabitschDepartment of Medicine I, Stem Cell Transplantation Unit, Medical University of Vienna, Vienna, Austria.
Marija BojicDepartment of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Sahra PajendaDepartment of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Roman Reindl-SchwaighoferDepartment of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Wolfgang WinnickiDepartment of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Andreas VychytilDepartment of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Hanna A KnausDepartment of Medicine I, Stem Cell Transplantation Unit, Medical University of Vienna, Vienna, Austria.
Rainer OberbauerDepartment of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Kurt DerflerDepartment of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.
Philipp WohlfarthDepartment of Medicine I, Stem Cell Transplantation Unit, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATHanusch Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pure red cell aplasia (PRCA) after ABO-incompatible allogeneic hematopoietic stem cell transplantation (HSCT) is caused by persisting host-derived isohemagglutinins directed against donor red blood cell (RBC) antigens. ABO antigen-specific immunoadsorption (ABO-IA) with Glycosorb®, commonly used for desensitization therapy in ABO-incompatible living donor renal transplantation, specifically eliminates circulating isohemagglutinins and might represent a novel treatment option for post-HSCT PRCA. In this prospective observational (

Indexed as

Glycosorb®hematopoeietic stem cell transplantationimmunoadsorptionisohemagglutininspure red blood cell aplasia (PRCA)

Identifiers

PMID33195341
PMCPMC7642244
OpenAlexW3087540314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.