Evidence map›Paper›PMID 33195292›Full record

ArticleFrontiers in medicine2020

Unexpected Acceleration in Treprostinil Delivery Administered by a Lenus Pro® Implantable Pump in Two Patients Treated for Pulmonary Arterial Hypertension.

Garance Kopp, Anne-Lise Hachulla, Stéphane Noble, Aurélien Bringard, Paola M Soccal, Maurice Beghetti, Frédéric Lador

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Garance KoppDivision of Pneumology, University Hospitals of Geneva, Genève, Switzerland.
Anne-Lise HachullaDivision of Radiology, University Hospitals of Geneva, Genève, Switzerland.
Stéphane NoblePulmonary Hypertension Program, University Hospitals of Geneva, Genève, Switzerland.
Aurélien BringardDivision of Pneumology, University Hospitals of Geneva, Genève, Switzerland.
Paola M SoccalDivision of Pneumology, University Hospitals of Geneva, Genève, Switzerland.
Maurice BeghettiPulmonary Hypertension Program, University Hospitals of Geneva, Genève, Switzerland.
Frédéric LadorDivision of Pneumology, University Hospitals of Geneva, Genève, Switzerland.
University of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravenous treprostinil administration by an implantable pump is an attractive option for pulmonary arterial hypertension (PAH) treatment and is the subject of recent publications. Short-term studies are promising, but there is still a lack of long-term prospective data. We analyzed the treprostinil flow rate administered by the Lenus Pro® implantable pump in 2 patients suffering from PAH during follow-up times of respectively 4.2 and 3 years. The flow rate delivered by the pumps in these 2 patients exceeded the manufacturer admitted margin of error within 2 years and continued to increase to reach, respectively, 158 and 120% of the expected flow rate at the end of the follow up. In one case, the implantable pump had to be removed for this reason. The

Indexed as

implantable pumpinternal deviceprostacyclin analogspulmonary arterial hypertensiontreprostinil delivery

Identifiers

PMID33195292
PMCPMC7662390
OpenAlexW3096219071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.