Evidence map›Paper›PMID 33195164›Full record

ReviewFrontiers in bioengineering and biotechnology2020

Recent Advances in Self-Exciting Photodynamic Therapy.

Nicholas Thomas Blum, Yifan Zhang, Junle Qu, Jing Lin, Peng Huang

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
  2. Self-illuminating liposome-derivedActa pharmaceutica Sinica. B · 2025
    Article
  3. Review
  4. Laser-Free Photosensitive Systems in Cancer Therapy: A Comprehensive Review.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Internal light source for deep photodynamic therapy.Light, science & applications · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nicholas Thomas BlumMarshall Laboratory of Biomedical Engineering, Laboratory of Evolutionary Theranostics (LET), International Cancer Center, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, China.
Yifan ZhangMarshall Laboratory of Biomedical Engineering, Laboratory of Evolutionary Theranostics (LET), International Cancer Center, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, China.
Junle QuKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, China.
Jing LinMarshall Laboratory of Biomedical Engineering, Laboratory of Evolutionary Theranostics (LET), International Cancer Center, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, China.
Peng HuangMarshall Laboratory of Biomedical Engineering, Laboratory of Evolutionary Theranostics (LET), International Cancer Center, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, China.
Shenzhen University Health Science Center · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) is already (Food and Drug Administration) FDA approved and used in the clinic for oncological treatment of pancreatic, lung, esophagus, bile duct, and of course several cancers of skin. It is an important tool in the oncological array of treatments, but for it exist several shortcomings, the most prominent of which is the shallow depth penetration of light within tissues. One-way researchers have attempted to circumvent this is through the creation of self-exciting "auto-PDT" nanoplatforms, which do not require the presence of an external light source to drive the PDT process. Instead, these platforms are driven either through oxidative chemical excitation in the form of chemiluminescence or radiological excitation from beta-emitting isotopes in the form of Cherenkov luminescence. In both, electronic excitations are generated and then transferred to the photosensitizer (PS)

Indexed as

bioluminescencecancerCerenkovchemiluminescencenanoplatformphotodynamic therapyROS

Identifiers

PMID33195164
PMCPMC7606875
OpenAlexW3094586429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.