Evidence map›Paper›PMID 33195139›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Biocompatibility of a Conjugated Polymer Retinal Prosthesis in the Domestic Pig.

José Fernando Maya-Vetencourt, Stefano Di Marco, Maurizio Mete, Mattia Di Paolo, Domenico Ventrella, Francesca Barone, Alberto Elmi, Giovanni Manfredi, Andrea Desii, Walter G Sannita and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pig Models in Retinal Research and Retinal Disease.Cold Spring Harbor perspectives in medicine · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Neuromodulation using electroosmosis.Journal of neural engineering · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

José Fernando Maya-VetencourtCenter for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genova, Italy.
Stefano Di MarcoCenter for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genova, Italy.
Maurizio MeteDepartment of Ophthalmology, Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Mattia Di PaoloDepartment of Biotechnology and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.
Domenico VentrellaDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Francesca BaroneDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Alberto ElmiDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Giovanni ManfrediCenter for Nano Science and Technology, Istituto Italiano di Tecnologia, Milan, Italy.
Andrea DesiiCenter for Nano Science and Technology, Istituto Italiano di Tecnologia, Milan, Italy.
Walter G SannitaCenter for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genova, Italy.
Silvia BistiDepartment of Biotechnology and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.
Guglielmo LanzaniCenter for Nano Science and Technology, Istituto Italiano di Tecnologia, Milan, Italy.
Grazia PertileDepartment of Ophthalmology, Sacro Cuore Don Calabria Hospital, Negrar, Italy.
Maria Laura BacciDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Fabio BenfenatiCenter for Synaptic Neuroscience and Technology, Istituto Italiano di Tecnologia, Genova, Italy.
University of Bologna · ITCenter for Nano Science and Technology · ITItalian Institute of Technology · ITOspedale Sacro Cuore Don Calabria · ITUniversity of L'Aquila · ITIstituto Nazionale Biostrutture e Biosistemi · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progressive degeneration of retinal photoreceptors is one of the most significant causes of blindness in humans. Conjugated polymers represent an attractive solution to the field of retinal prostheses, and a multi-layer fully organic prosthesis implanted subretinally in dystrophic Royal College of Surgeons (RCS) rats was able to rescue visual functions. As a step toward human translation, we report here the fabrication and

Indexed as

biomedical pigconjugated polymersretinal degenerationretinal prosthesisretinitis pigmentosa

Identifiers

PMID33195139
PMCPMC7605258
OpenAlexW3092683805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.