Evidence map›Paper›PMID 33195124›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Holistic Approach of Swiss Fetal Progenitor Cell Banking: Optimizing Safe and Sustainable Substrates for Regenerative Medicine and Biotechnology.

Alexis Laurent, Nathalie Hirt-Burri, Corinne Scaletta, Murielle Michetti, Anthony S de Buys Roessingh, Wassim Raffoul, Lee Ann Applegate

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

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  12. Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs.Journal of burn care & research : official publication of the American Burn Association · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alexis LaurentRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, Épalinges, Switzerland.
Nathalie Hirt-BurriRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, Épalinges, Switzerland.
Corinne ScalettaRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, Épalinges, Switzerland.
Murielle MichettiRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, Épalinges, Switzerland.
Anthony S de Buys RoessinghChildren and Adolescent Surgery Service, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Wassim RaffoulPlastic, Reconstructive and Hand Surgery Service, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Lee Ann ApplegateRegenerative Therapy Unit, Lausanne University Hospital, University of Lausanne, Épalinges, Switzerland.
University of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Safety, quality, and regulatory-driven iterative optimization of therapeutic cell source selection has constituted the core developmental bedrock for primary fetal progenitor cell (FPC) therapy in Switzerland throughout three decades. Customized Fetal Transplantation Programs were pragmatically devised as straightforward workflows for tissue procurement, traceability maximization, safety, consistency, and robustness of cultured progeny cellular materials. Whole-cell bioprocessing standardization has provided plethoric insights into the adequate conjugation of modern biotechnological advances with current restraining legislative, ethical, and regulatory frameworks. Pioneer translational advances in cutaneous and musculoskeletal regenerative medicine continuously demonstrate the therapeutic potential of FPCs. Extensive technical and clinical hindsight was gathered by managing pediatric burns and geriatric ulcers in Switzerland. Concomitant industrial transposition of dermal FPC banking, following good manufacturing practices, demonstrated the extensive potential of their therapeutic value. Furthermore,

Indexed as

biotechnologycell therapyclinical cell bankingfetal cell transplantationprimary fetal progenitor cellsregenerative medicine

Identifiers

PMID33195124
PMCPMC7644790
OpenAlexW3093813118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.