ArticleFrontiers in chemistry2020
Reactions of Medicinal Gold(III) Compounds With Proteins and Peptides Explored by Electrospray Ionization Mass Spectrometry and Complementary Biophysical Methods.
Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed, 54 citations in OpenAlex.
- Article
- Competitive LC-MS/MS assay to investigate protein metalation dynamics.Inorganic chemistry frontiers · 2026Article
- Thiosugar-functionalized gold(I)-NHC complexes as selective anticancer agents for potential targeted therapy.Frontiers in chemistry · 2026Article
- Article
- Study of metalation of thioredoxin by gold(I) therapeutic compounds using combined liquid chromatography/capillary electrophoresis with inductively coupled plasma/electrospray MS/MS detection.Analytical and bioanalytical chemistry · 2024Article
- Some remarks on the biological application of gold(III) complexes.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Article
- Recent Advances in Metalloproteomics.Biomolecules · 2024Review
- Thioredoxin Reductase and Organometallic Complexes: A Pivotal System to Tackle Multidrug Resistant Tumors?Cancers · 2023Review
- Protein Metalation by Medicinal Gold Compounds: Identification of the Main Features of the Metalation Process through ESI MS Experiments.Molecules (Basel, Switzerland) · 2023Review
- Next Generation Gold Drugs and Probes: Chemistry and Biomedical Applications.Chemical reviews · 2023Review
- Binding Modes of a Cytotoxic Dinuclear Copper(II) Complex with Phosphate Ligands Probed by Vibrational Photodissociation Ion Spectroscopy.Inorganic chemistry · 2023Article
- Chemical Modification of Auranofin Yields a New Family of Anticancer Drug Candidates: The Gold(I) Phosphite Analogues.Molecules (Basel, Switzerland) · 2023Article
- Large Protein Assemblies for High-Relaxivity Contrast Agents: The Case of Gadolinium-Labeled Asparaginase.Bioconjugate chemistry · 2022Article
- Reactions of proteins with a few organopalladium compounds of medicinal interest.RSC advances · 2022Article
- Anti-Staphylococcal Activity of the Auranofin Analogue Bearing Acetylcysteine in Place of the Thiosugar: An Experimental and Theoretical Investigation.Molecules (Basel, Switzerland) · 2022Article
- A CFrontiers in microbiology · 2022Article
- Determination of Relative Stabilities of Metal-Peptide Bonds in the Gas Phase.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Targeting Zinc Finger Proteins with Exogenous Metals and Molecules: Lessons learned from Tristetraprolin, a CCCH type Zinc Finger.European journal of inorganic chemistry · 2021Article
- Anticancer Diiron Vinyliminium Complexes: A Structure-Activity Relationship Study.Pharmaceutics · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrospray ionization mass spectrometry (ESI MS) is a powerful investigative tool to analyze the reactions of metallodrugs with proteins and peptides and characterize the resulting adducts. Here, we have applied this type of approach to four experimental anticancer gold(III) compounds for which extensive biological and mechanistic data had previously been gathered, namely, Auoxo6, Au
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.