Evidence map›Paper›PMID 33195032›Full record

ArticleFrontiers in chemistry2020

Mechanistic Insights Into the Anticancer Properties of the Auranofin Analog Au(PEt

Iogann Tolbatov, Damiano Cirri, Lorella Marchetti, Alessandro Marrone, Cecilia Coletti, Nazzareno Re, Diego La Mendola, Luigi Messori, Tiziano Marzo, Chiara Gabbiani and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Multifunctional auranofin analogues: dual-targeting TSPO/TrxR gold(I) complexes with activity in resistant ovarian cancer.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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  12. Anticancer effects against colorectal cancer models of chloro(triethylphosphine)gold(I) encapsulated in PLGA-PEG nanoparticles.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Iogann TolbatovDepartment of Pharmacy, University "G. D'Annunzio" Chieti-Pescara, Chieti, Italy.
Damiano CirriDepartment of Chemistry and Industrial Chemistry (DCCI), University of Pisa, Pisa, Italy.
Lorella MarchettiDepartment of Chemistry and Industrial Chemistry (DCCI), University of Pisa, Pisa, Italy.
Alessandro MarroneDepartment of Pharmacy, University "G. D'Annunzio" Chieti-Pescara, Chieti, Italy.
Cecilia ColettiDepartment of Pharmacy, University "G. D'Annunzio" Chieti-Pescara, Chieti, Italy.
Nazzareno ReDepartment of Pharmacy, University "G. D'Annunzio" Chieti-Pescara, Chieti, Italy.
Diego La MendolaDepartment of Pharmacy, University of Pisa, Pisa, Italy.
Luigi MessoriLaboratory of Metals in Medicine (MetMed), Department of Chemistry "U. Schiff", University of Florence, Florence, Italy.
Tiziano MarzoDepartment of Pharmacy, University of Pisa, Pisa, Italy.
Chiara GabbianiDepartment of Chemistry and Industrial Chemistry (DCCI), University of Pisa, Pisa, Italy.
Alessandro PratesiDepartment of Chemistry and Industrial Chemistry (DCCI), University of Pisa, Pisa, Italy.
University of Pisa · ITUniversity of Chieti-Pescara · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Au(PEt

Indexed as

31PNMRauranofincancerDFTESI-MSgoldmetal-based anticancer drugsprotein metalation

Identifiers

PMID33195032
PMCPMC7531625
OpenAlexW3087570543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.