Evidence map›Paper›PMID 33194964›Full record

ReviewFrontiers in public health2020

Trends in MERS-CoV, SARS-CoV, and SARS-CoV-2 (COVID-19) Diagnosis Strategies: A Patent Review.

José Adão Carvalho Nascimento Junior, Anamaria Mendonça Santos, Ana Maria Santos Oliveira, Adriana Gibara Guimarães, Lucindo José Quintans-Júnior, Henrique Douglas Melo Coutinho, Natália Martins, Lysandro Pinto Borges, Mairim Russo Serafini

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Observational
  5. Global landscape of patents related to human coronaviruses.International journal of biological sciences
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

José Adão Carvalho Nascimento JuniorDepartment of Pharmacy, Federal University of Sergipe, São Cristovão, Brazil.
Anamaria Mendonça SantosDepartment of Pharmacy, Federal University of Sergipe, São Cristovão, Brazil.
Ana Maria Santos OliveiraDepartment of Pharmacy, Federal University of Sergipe, São Cristovão, Brazil.
Adriana Gibara GuimarãesDepartment of Pharmacy, Federal University of Sergipe, São Cristovão, Brazil.
Lucindo José Quintans-JúniorDepartment of Pharmacy, Federal University of Sergipe, São Cristovão, Brazil.
Henrique Douglas Melo CoutinhoLaboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri-URCA, Crato, Brazil.
Natália MartinsFaculty of Medicine, University of Porto, Porto, Portugal.
Lysandro Pinto BorgesDepartment of Pharmacy, Federal University of Sergipe, São Cristovão, Brazil.
Mairim Russo SerafiniDepartment of Pharmacy, Federal University of Sergipe, São Cristovão, Brazil.
Universidade Federal de Sergipe · BRi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTUniversidade Regional do Cariri · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of a new coronavirus (SARS-CoV-2) outbreak represents a challenge for the diagnostic laboratories responsible for developing test kits to identify those infected with SARS-CoV-2. Methods with rapid and accurate detection are essential to control the sources of infection, to prevent the spread of the disease and to assist decision-making by public health managers. Currently, there is a wide variety of tests available with different detection methodologies, levels of specificity and sensitivity, detection time, and with an extensive range of prices. This review therefore aimed to conduct a patent search in relation to tests for the detection of SARS-CoV, MERS-CoV, and SARS-CoV-2. The greatest number of patents identified in the search were registered between 2003 and 2011, being mainly deposited by China, the Republic of Korea, and the United States. Most of the patents used the existing RT-PCR, ELISA, and isothermal amplification methods to develop simple, sensitive, precise, easy to use, low-cost tests that reduced false-negative or false-positive results. The findings of this patent search show that an increasing number of materials and diagnostic tests for the coronavirus are being produced to identify infected individuals and combat the growth of the current pandemic; however, there is still a question in relation to the reliability of the results of these tests.

Indexed as

COVID-19Middle East Respiratory Syndrome CoronavirusChinaHumansReproducibility of ResultsRepublic of KoreaSARS-CoV-2Sensitivity and Specificitycoronavirus (2019-nCoV)COVID-19 (condition)ELISA (enzyme linked immuno sorbent assay)isothermal amplificationMERS (middle east respiratory syndrome)RT-PCR—polymerase chain reaction with reverse transcriptionSARS

Identifiers

PMID33194964
PMCPMC7653175
OpenAlexW3096572571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.