Evidence map›Paper›PMID 33194959›Full record

ArticleFrontiers in public health2020

Blood Transcriptome Response to Environmental Metal Exposure Reveals Potential Biological Processes Related to Alzheimer's Disease.

Julian Krauskopf, Ingvar A Bergdahl, Anders Johansson, Domenico Palli, Thomas Lundh, Soterios A Kyrtopoulos, Theo M de Kok, Jos C Kleinjans

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Guilingji capsule for Alzheimer's disease: secondary analysis of a randomized non-inferiority controlled trial.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Julian KrauskopfDepartment of Toxicogenomics, Maastricht University, Maastricht, Netherlands.
Ingvar A BergdahlSection of Sustainable Health, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Anders JohanssonOdontology, Umeå University, Umeå, Sweden.
Domenico PalliCancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network - ISPRO, Florence, Italy.
Thomas LundhDivision of Occupational and Environmental Medicine, Lund University Hospital, Lund, Sweden.
Soterios A KyrtopoulosInstitute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece.
Theo M de KokDepartment of Toxicogenomics, Maastricht University, Maastricht, Netherlands.
Jos C KleinjansDepartment of Toxicogenomics, Maastricht University, Maastricht, Netherlands.
Maastricht University · NLUmeå University · SELund University · SENational Hellenic Research Foundation · GRPiedmont Reference Center for Epidemiology and Cancer Prevention · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease which is manifested by a progressive and irreversible decline of cognition, memory loss, a shortened attention span, and changes in personality. Aging and genetic pre-dispositions, particularly the presence of a specific form of apolipoprotein E (

Indexed as

Alzheimer DiseaseBiological PhenomenaNeurodegenerative DiseasesEnvironmental ExposureFemaleHumansMaleTranscriptomeAlzheimer's diseaseAPOEgene expressionmetalsmicroarraytranscriptomics

Identifiers

PMID33194959
PMCPMC7609776
OpenAlexW3094117200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.