Evidence map›Paper›PMID 33194842›Full record

ArticleFrontiers in cellular and infection microbiology2020

BLIMP-1 Mediated Downregulation of TAK1 and p53 Molecules Is Crucial in the Pathogenesis of

Gundappa Saha, Adarsh Kumar Chiranjivi, Bakulesh M Khamar, Kumari Prerna, Manish Kumar, Vikash Kumar Dubey

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Gundappa SahaDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, India.
Adarsh Kumar ChiranjiviDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, India.
Bakulesh M KhamarResearch & Development, Cadila Pharmaceuticals Limited, Ahmedabad, India.
Kumari PrernaSchool of Biochemical Engineering, Indian Institute of Technology Banaras Hindu University (BHU), Varanasi, India.
Manish KumarDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, India.
Vikash Kumar DubeySchool of Biochemical Engineering, Indian Institute of Technology Banaras Hindu University (BHU), Varanasi, India.
Indian Institute of Technology Guwahati · INBanaras Hindu University · INCadila Pharmaceuticals (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise regulation of inflammasome is critical during any pathogenic encounter. The whole innate immune system comprising of pattern recognition receptors (PRRs) relies on its ability to sense microbes. The fate of cellular death in infected cells depends mostly on the activation of these inflammasome, the dysregulation of which, due to functional manipulation by various pathogens, leads to be the cause of many human diseases. Here, an interesting finding has been observed which is related to how

Indexed as

Leishmania donovaniLeishmaniasis, VisceralDown-RegulationHumansMAP Kinase Kinase Kinase 7MAP Kinase Kinase KinasesPositive Regulatory Domain I-Binding Factor 1PyroptosisTumor Suppressor Protein p53MAP Kinase Kinase Kinase 7MAP Kinase Kinase KinasesPositive Regulatory Domain I-Binding Factor 1PRDM1 protein, humanTP53 protein, humanTumor Suppressor Protein p53BLIMP-1immuno-suppressionkala-azarLeishmaniasismacrophage

Identifiers

PMID33194842
PMCPMC7658262
OpenAlexW3096866931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.