Evidence map›Paper›PMID 33194637›Full record

ArticleFrontiers in oncology2020

MicroRNA-1269a Promotes Proliferation and Arrest of Apoptosis of Glioma Cells by Directly Targeting ATRX.

Yulian Zhang, Qi Wang, Na Luo, Jiang Liu, Hongxiang Ren, Xu Shao, Li Zhang, Yanbing Yu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  6. Article
  7. miR-1269a and miR-1269b: Emerging Carcinogenic Genes of the miR-1269 Family.Frontiers in cell and developmental biology · 2022
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yulian ZhangDepartment of Neurosurgery, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China.
Qi WangDepartment of Neurosurgery, China-Japan Friendship Hospital, Beijing, China.
Na LuoDepartment of Neurosurgery, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China.
Jiang LiuDepartment of Neurosurgery, China-Japan Friendship Hospital, Beijing, China.
Hongxiang RenDepartment of Neurosurgery, China-Japan Friendship Hospital, Beijing, China.
Xu ShaoDepartment of Neurosurgery, China-Japan Friendship Hospital, Beijing, China.
Li ZhangDepartment of Neurosurgery, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China.
Yanbing YuDepartment of Neurosurgery, Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China.
China-Japan Friendship Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma is one of the deadliest malignant brain tumors in adults worldwide. MicroRNA (miR) has been reported to be a pivotal regulator in human tumors. The aim of this study was to determine the expression, function, and mechanism of action of miR-1269a in glioma progression. The expression of miR-1269a was higher in both glioma cases reported in databases and glioma cell lines, and it was highly associated with poorer prognosis. Next, it was shown

Indexed as

apoptosisATRXgliomamiR-1269aprognosisproliferationtarget

Identifiers

PMID33194637
PMCPMC7659443
OpenAlexW3095927180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.