Evidence map›Paper›PMID 33194538›Full record

ArticleJournal of obsessive-compulsive and related disorders2020

Dimensions of interoception in obsessive-compulsive disorder.

Goi Khia Eng, Katherine A Collins, Carina Brown, Molly Ludlow, Russell H Tobe, Dan V Iosifescu, Emily R Stern

Abstract read
In one paragraph

Article in Journal of obsessive-compulsive and related disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Associations Between Suicidality and Interoception in Obsessive-Compulsive Disorder.Journal of obsessive-compulsive and related disorders · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Goi Khia EngDepartment of Psychiatry, New York University School of Medicine, New York, NY.
Katherine A CollinsNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY.
Carina BrownDepartment of Psychiatry, New York University School of Medicine, New York, NY.
Molly LudlowNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY.
Russell H TobeNathan S. Kline Institute for Psychiatric Research, Orangeburg, NY.
Dan V IosifescuDepartment of Psychiatry, New York University School of Medicine, New York, NY.
Emily R SternDepartment of Psychiatry, New York University School of Medicine, New York, NY.

Funding

Neurobiology of sensory phenomena in obsessive-compulsive disorderR01MH111794 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI STERN, EMILY R · 2017 to 2021
$3.0M
The effects of ondansetron on neural systems and symptoms associated with sensory phenomenaR33MH107589 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI STERN, EMILY R · 2017 to 2019
$1.4M
The effects of ondansetron on neural systems and symptoms associated with sensory phenomenaR21MH107589 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI STERN, EMILY R · 2015 to 2016
$922k
NIMH NIH HHS R01 MH111794NIMH NIH HHS R21 MH107589NIMH NIH HHS R33 MH107589
6 · The paper itself

Abstract

Interoceptive sensibility (IS) refers to the subjective experience of perceiving and being aware of one's internal body sensations, and is typically evaluated using self-report questionnaires or confidence ratings. Here we evaluated IS in 81 patients with OCD and 76 controls using the Multidimensional Scale of Interoceptive Awareness (MAIA), which contains 8 subscales assessing adaptive and maladaptive responses to sensation. Compared to controls, OCD patients showed hyperawareness of body sensations. Patients also demonstrated a more maladaptive profile of IS characterized by greater distraction from and worry about unpleasant sensations, and reduced tendency to experience the body as safe and trustworthy. These findings were independent of medication status and comorbidities in the patient group. Correlational analyses showed that subscales of the MAIA were differentially associated with OCD symptom dimensions. These findings indicate that patients with OCD show abnormality of IS that is independent of confounding factors related to medication and comorbidities and associated with different OCD symptom dimensions. Future work would benefit from examining neural correlates of these effects and evaluating whether dimensions of IS are impacted by treatments for the disorder.

Identifiers

PMID33194538
PMCPMC7665060

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.