Evidence map›Paper›PMID 33194364›Full record

ArticlePeerJ2020

Cytotoxic effect of

Carol Haddoub, Mohamad Rima, Sandrine Heurtebise, Myriam Lawand, Dania Jundi, Riyad Sadek, Sebastian Amigorena, Ziad Fajloun, Marc C Karam

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Effect ofMolecules (Basel, Switzerland) · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Carol Haddoub *Department of Biology, University of Balamand, Kalhat, Al-Kurah, Lebanon.
Mohamad Rima *Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM, CNRS, University of Strasbourg, Strasbourg, France.
Sandrine HeurtebiseInstitut Curie, INSERM U932, PSL Research University, Paris, France.
Myriam LawandInstitut Curie, INSERM U932, PSL Research University, Paris, France.
Dania JundiLAB3B, Doctoral School for Sciences and Technology, Azm Centre for Research in Biotechnology, Lebanese University, Tripoli, Lebanon.
Riyad SadekDepartment of Biology, American University of Beirut, Beirut, Lebanon.
Sebastian AmigorenaInstitut Curie, INSERM U932, PSL Research University, Paris, France.
Ziad FajlounLAB3B, Doctoral School for Sciences and Technology, Azm Centre for Research in Biotechnology, Lebanese University, Tripoli, Lebanon.
Marc C KaramDepartment of Biology, University of Balamand, Kalhat, Al-Kurah, Lebanon.
Inserm · FRCentre National de la Recherche Scientifique · FRUniversity of Balamand · LBAmerican University of Beirut · LBLebanese University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsThe toxicity of the venom on B16 and MCA cells was assessed using flow cytometry and xCELLigence assays. For in vivo testing, tumor growth was followed in mice after intratumoral venom injection.

resultsThe venom toxicity showed a dose-dependent cell death on both B16 and MCA cells. Interestingly, overexpression of ovalbumin increased the sensitivity of the cells to the venom. However, the venom was not able to eradicate induced-tumor growth when injected at 100 µg/kg. Our study demonstrates a cytotoxic effect of

Indexed as

Anti-cancer activityB16 cellsIn vivoMCA cellsMontivipera bornmuelleri

Identifiers

PMID33194364
PMCPMC7597635
OpenAlexW3096900591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.