Evidence map›Paper›PMID 33194303›Full record

ArticleProceedings. IEEE International Conference on Bioinformatics and Biomedicine2019

Deep Learning Prediction of Mild Cognitive Impairment using Electronic Health Records.

Sajjad Fouladvand, Michelle M Mielke, Maria Vassilaki, Jennifer St Sauver, Ronald C Petersen, Sunghwan Sohn

Abstract read
In one paragraph

Article in Proceedings. IEEE International Conference on Bioinformatics and Biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Causal Explanation from Mild Cognitive Impairment Progression using Graph Neural Networks.Proceedings. IEEE International Conference on Bioinformatics and Biomedicine · 2024
    Article
  7. Article
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  14. Article
  15. Mild Cognitive Impairment: Data-Driven Prediction, Risk Factors, and Workup.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2023
    Article
  16. Detection of Dementia Signals from Longitudinal Clinical Visits Using One-Class Classification.Proceedings. IEEE International Conference on Healthcare Informatics · 2022
    Article
  17. Article
  18. Article
  19. Early Alert of Elderly Cognitive Impairment using Temporal Streaming Clustering.Proceedings. IEEE International Conference on Bioinformatics and Biomedicine · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sajjad FouladvandDepartment of Computer Science, Institute for Biomedical Informatics, University of Kentucky, Lexington, KY, USA.
Michelle M MielkeDivision of Epidemiology, Department of Neurology, Mayo Clinic, Rochester, MN USA.
Maria VassilakiDivision of Epidemiology, Mayo Clinic, Rochester, MN USA.
Jennifer St SauverDivision of Epidemiology, Mayo Clinic, Rochester, MN USA.
Ronald C PetersenDepartment of Neurology, Mayo Clinic, Rochester, MN USA.
Sunghwan SohnDivision of Digital Health Sciences, Mayo Clinic, Rochester, MN USA.

Funding

SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI PETERSEN, RONALD C · 1999 to 2018
$36.9M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
Secondary use of EMR for residency training in asthma care and documentationR21AI142702 · NIAID · MAYO CLINIC ROCHESTER · PI JUHN, YOUNG J, SOHN, SUNGHWAN · 2019 to 2020
$437k
NIAID NIH HHS R21 AI142702NIA NIH HHS P50 AG016574NIA NIH HHS R01 AG034676NIA NIH HHS R33 AG058738NIA NIH HHS U01 AG006786
6 · The paper itself

Abstract

About 44.4 million people have been diagnosed with dementia worldwide, and it is estimated that this number will be almost tripled by 2050. Predicting mild cognitive impairment (MCI), an intermediate state between normal cognition and dementia and an important risk factor for the development of dementia is crucial in aging populations. MCI is formally determined by health professionals through a comprehensive cognitive evaluation, together with a clinical examination, medical history and often the input of an informant (an individual that know the patient very well). However, this is not routinely performed in primary care visits, and could result in a significant delay in diagnosis. In this study, we used deep learning and machine learning techniques to predict the progression from cognitively unimpaired to MCI and also to analyze the potential for patient clustering using routinely-collected electronic health records (EHRs). Our analysis of EHRs indicates that temporal characteristics of patient data incorporated in a deep learning model provides increased power in predicting MCI.

Indexed as

Alzheimer’s diseasedeep learningdementiamachine learningmild cognitive impairmentrecurrent neural networks

Identifiers

PMID33194303
PMCPMC7665163

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.