Evidence map›Paper›PMID 33194285›Full record

ArticleSurgical neurology international2020

Impact of local treatment on survival from hematological malignancies causing spinal cord compression.

Hela Ghedira, Khaled Radhouane, Essia Mezni, Safia Yahiaoui, Hela Stambouli, Mohamed Dehmani Yedeas, Asma Belaid, Chiraz Ammar, Karima Kacem, Samy Zriba and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Hela GhediraDepartment of Hematology Bab Saadoun, Tunis, Tunisia.
Khaled RadhouaneDepartment of Neurosurgery, Military Hospital of Tunis, Bab Saadoun, Tunis, Tunisia.
Essia MezniDepartment of Hematology Bab Saadoun, Tunis, Tunisia.
Safia YahiaouiDepartment of Radiotherapy, Salah Azaiez Institue, Bab Saadoun, Tunis, Tunisia.
Hela StambouliDepartment of Hematology Bab Saadoun, Tunis, Tunisia.
Mohamed Dehmani YedeasDepartment of Neurosurgery, Military Hospital of Tunis, Bab Saadoun, Tunis, Tunisia.
Asma BelaidDepartment of Radiotherapy, Salah Azaiez Institue, Bab Saadoun, Tunis, Tunisia.
Chiraz AmmarDepartment of Radiotherapy, Salah Azaiez Institue, Bab Saadoun, Tunis, Tunisia.
Karima KacemDepartment of Hematology, Aziza Othmana University Hospital, Faculty of Medecine of Tunis, University Tunis El Manar, Bab Saadoun, Tunis, Tunisia.
Samy ZribaDepartment of Hematology Bab Saadoun, Tunis, Tunisia.
Fehmi MsadekDepartment of Hematology Bab Saadoun, Tunis, Tunisia.
Mondher YedeasDepartment of Neurosurgery, Military Hospital of Tunis, Bab Saadoun, Tunis, Tunisia.
Ahmed HarbaouiDepartment of Neurosurgery, Military Hospital of Tunis, Bab Saadoun, Tunis, Tunisia.
Ridha ChkiliDepartment of Neurosurgery, Military Hospital of Tunis, Bab Saadoun, Tunis, Tunisia.
Stony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVarious hematological malignancies, including multiple myeloma, plasmacytoma, aggressive lymphoma, and indolent lymphoma, rarely result in spinal cord compression.

methodsHere, we retrospectively analyzed 32 patients with multiple myeloma (50%), plasmacytoma (13%), aggressive lymphoma (28%), and indolent lymphoma (9%), resulting in spinal cord compression (2004 and 2016). Patients averaged 57 years of age and presented with the indolent onset of spinal cord compression (91% of cases) resulting mostly in motor deficits (69%).

resultsLocal treatment modalities included radiotherapy (RT) (28%) alone, decompressive surgery (28%) alone, or decompressive surgery with consolidation RT (40%). The 1-year overall survival was 70%, and the progression-free survival frequency was 62%.

conclusionThis study highlighted the importance of standardizing the indications for RT alone versus RT with surgery depending on the patient's underlying pathological diagnosis, neurological deficits, and radiological findings.

Indexed as

ChemotherapyHematological malignancyRadiotherapySpinal cord compressionSurgery

Identifiers

PMID33194285
PMCPMC7656002
OpenAlexW3094263584

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.